Korean J Dermatol.  2012 May;50(5):464-467.

Systematized Inflammatory Linear Verrucous Epidermal Nevus

• Namkoong S
• Kim JS
• Kim JY
• Gye J
• Chung J
• Choi HI
• Hong SP
• Park BC
• Kim M

Abstract

Inflammatory linear verrucous epidermal nevi (ILVEN) were first described in the literature, in 1971, by Altman and Mehregan. Most cases were reported as solitary lesions. In contrast, systematized ILVEN, involving wide areas of the integument, has only rarely been reported. A variety of treatment modalities has been reported, ranging from topical medications, such as potent corticosteroids or tretinoin 0.1% to variable procedures, including CO2 and pulsed dye laser, cryotherapy, and surgical excision. However, multifocal skin lesion is more difficult to treat. An 8-year old boy was presented with an extensive thick scaly plaques and patches, affecting the trunk and the four extremities sparing face. It developed when he was 3 years old, and he complained pruritus. On physical examination, linear, or whirl-like scaly plaques were seen, along with Blaschko lines. Pathologic finding was in accordance to ILVEN. We treated him with topical calcipotriol, tacrolimus and systemic acitretin. After 8 months, the lesion and symptoms improved.

Keyword

Blaschko line; Calcipotriol; Inflammatory linear verrucous epidermal nevus; Tacrolimus

MeSH Terms

Acitretin
Adrenal Cortex Hormones
Calcitriol
Cryotherapy
Extremities
Lasers, Dye
Nevus
Nevus, Sebaceous of Jadassohn
Physical Examination
Pruritus
Skin
Tacrolimus
Tretinoin
Acitretin
Adrenal Cortex Hormones
Calcitriol
Tacrolimus
Tretinoin