Korean J Gynecol Oncol Colposc.  2001 Sep;12(3):254-258.

Elevated Serum Alpha-Fetoprotein Associated with Sertoli-Leydig Cell Tumor of Ovary

Affiliations
  • 1Department of Obstetrics and Gynecology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
  • 2Department of Pathology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.

Abstract

A case of intermediate differentiated Sertoli-Leydig cell tumor with elevated Alpha-fetoprotein (AFP) levels occurred in a 15-year-old girl. No germ cell component and no heterologous elements were identified. Secretion of AFP by Sertoli-Leydig cell tumor has rarely been mentioned previously, and its mechanism is difficult to explain. We present this case with review of related literatures.

Keyword

Alpha-fetoprotein; Sertoli-Leydig cell tumor; AFP
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