Korean J Anesthesiol.  2004 Jul;47(1):17-22. 10.4097/kjae.2004.47.1.17.

Effects of Enflurane on Pulse Transit Time

• Baik SW
• Park YS
• Yae SY
• Jeon GR
• Choi BC
• Jung DK

• KMID: 2237550
• DOI: http://doi.org/10.4097/kjae.2004.47.1.17

Abstract

BACKGROUND: In Anesthetic state, many hemodynamic parameters including blood pressure, heart rate and arterial compliance are changed. Moreover pulse transit time (PTT) is influenced by heart rate, blood pressure changes, and the compliance of the arteries.
METHODS
In this study, we investigated PTT changes in patients under enflurane anesthesia. PTT of the finger was measured by photoplethysmography (PPG) and electrocardiography (ECG). PTT values were calculated as the time interval between the peak of the ECG R wave and the peak of the second derivatived of the PPG in the finger tip.
RESULTS
ECG amplitude and heart rate increased reflecting hemodynamic chnages after enflurane anesthesia, and the PTT increased after enflurane anesthesia treatment by 16.68 ms (n = 24). Moreover, PTT was found to be inversely proportion to aging.
CONCLUSIONS
The increase of PTT in the finger due to relaxation of the arterial wall muscle after enflurane anesthesia was used as an indicator of sympathetic block on muscle tone. This result suggests that PTT is strongly related with anesthetic state. And PTT may be one of useful surrogative methods for anesthetic monitoring, but PTT is unfortunately only qualitative.

Keyword

anesthesia; enflurane; photoplethysmography; pulse transit time

MeSH Terms

Aging
Anesthesia
Arteries
Blood Pressure
Compliance
Electrocardiography
Enflurane*
Fingers
Heart Rate
Hemodynamics
Humans
Photoplethysmography
Pulse Wave Analysis*
Relaxation
Enflurane