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Future Directions in Coronary CT Angiography: CT-Fractional Flow Reserve, Plaque Vulnerability, and Quantitative Plaque Assessment

Kay FU, Canan A, Abbara S

Coronary computed tomography angiography (CCTA) is a well-validated and noninvasive imaging modality for the assessment of coronary artery disease (CAD) in patients with stable ischemic heart disease and acute coronary...
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Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve in Patients with Anomalous Origin of the Right Coronary Artery from the Left Coronary Sinus

Tang CX, Lu MJ, Schoepf JU, Tesche C, Bauer M, Nance J, Griffith P, Lu GM, Zhang LJ

OBJECTIVE: To examine the fractional flow reserve derived from computed tomographic angiography (CT-FFR) in patients with anomalous origin of the right coronary artery from the left coronary sinus (R-ACAOS) with...
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Association between Left Ventricular Systolic Dysfunction and Mortality in Patients with Septic Shock

Kim S, Lee JD, Kim BK, Kim YH, Kim JH

BACKGROUND: The impact of myocardial damage on the prognosis of patients with septic shock is not clearly elucidated because complex hemodynamic changes in sepsis obscure the direct relationship. We evaluated...
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Comparison of the trometamol-balanced solution with two other crystalloid solutions for fluid resuscitation of a rat hemorrhagic model

Ting WT, Chang RW, Wang CH, Chen YS, Lee JJ

Currently, the optimal resuscitation fluid remains debatable. Therefore, in the present study, we designed a trometamol-balanced solution (TBS) for use as a resuscitation fluid for hemorrhagic shock. Hemorrhagic shock was...
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Echocardiographic Screening Methods for Pulmonary Hypertension: A Practical Review

Jang AY, Shin MS

Pulmonary hypertension (PH) is a debilitating condition defined as mean pulmonary arterial pressure (mPAP) ≥ 25 mmHg. The importance of impaired right ventricular (RV) hemodynamics is increasingly being recognized in...
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The Incidence of Perioperative Stroke: Estimate Using State and National Databases and Systematic Review

Al-Hader R, Al-Robaidi K, Jovin T, Jadhav A, Wechsler L, Thirumala

BACKGROUND AND PURPOSE: Perioperative stroke remains a devastating complication after surgical procedures, due to hemodynamic and inflammatory changes that increase the risk of strokes within 30 days following surgery. We...
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Catastrophic catecholamine-induced cardiomyopathy rescued by extracorporeal membrane oxygenation in recurrent malignant pheochromocytoma

Min D

Pheochromocytoma (PCC) is a rare catecholamine-producing tumor with the incidence in hypertension of 0.1-0.6%. PCC crisis is an endocrine emergency that can lead to hemodynamic disturbance and organ failure such...
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Effects of Recumbent Angle during Cycling on Cerebral Blood Flow Velocity and Rate Pressure Product during Exercise and Recovery

Kim SD, Jeong IG, Koh YS, Lee HH

BACKGROUND: The cerebral blood flow velocity (CBFV) and rate pressure product (RPP) have been reported to benefit hemodynamics more during exercise in the recumbent position than during that in the...
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Effect of pralidoxime on coronary perfusion pressure during cardiopulmonary resuscitation in a pig model

Jung YH, Ryu DH, Jeung KW, Na JY, Lee DH, Lee BK, Heo T, Min YI

OBJECTIVE: Pralidoxime is widely used for the treatment of organophosphate poisoning. Multiple studies have reported its vasoconstrictive property, which may facilitate the restoration of spontaneous circulation (ROSC) after cardiac arrest...
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Effect of gemigliptin on cardiac ischemia/reperfusion and spontaneous hypertensive rat models

Nam DH, Park J, Park SH, Kim KS, Baek EB

Diabetes is associated with an increased risk of cardiovascular complications. Dipeptidyl peptidase-4 (DPP-IV) inhibitors are used clinically to reduce high blood glucose levels as an antidiabetic agent. However, the effect...
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Evaluation of Flow Pattern in the Ascending Aorta in Patients with Repaired Tetralogy of Fallot Using Four-Dimensional Flow Magnetic Resonance Imaging

Lee S, Kim YJ, Jung JW, Choi JY, Park HK, Shin YR, Choi BW

OBJECTIVE: To evaluate flow pattern characteristics in the ascending aorta (AA) with four-dimensional (4D)-flow MRI and to determine predictors of aortic dilatation late after tetralogy of Fallot (TOF) repair. MATERIALS AND...
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Dexmedetomidine: present and future directions

Lee S

Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties. Dexmedetomidine induces a unique sedative response, which shows an easy transition from sleep...
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Risk factors associated with inpatient cardiac arrest during emergency endotracheal intubation at general wards

Park C

BACKGROUND: Peri-intubation cardiac arrest (PICA) following emergent endotracheal intubation (ETI) is a rare, however, potentially preventable type of cardiac arrest. Limited published data have described factors associated with inpatient PICA...
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Effects site concentrations of propofol using target-controlled infusion in dental treatment under deep sedation among different intellectual disability types

Salinas Salmeron KS, Kim HJ, Seo KS

BACKGROUND: We aimed to assess the dose needed to achieve the propofol effect-site concentration using target-controlled infusion in intellectually disabled patients and to detail the most effective method for achieving...
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The New Cutoff Value of the Hepatic Venous Pressure Gradient on Predicting Long-Term Survival in Cirrhotic Patients

Kim TY, Suk KT, Jeong SW, Ryu T, Kim DJ, Baik SK, Sohn JH, Jeong WK, Choi E, Jang JY, Kim MY

BACKGROUND: This study aimed to determine the prognostic role of the categorized hemodynamic stage (HS) based on the hepatic venous pressure gradient (HVPG) in patients with portal hypertension. METHODS: Of 1,025...
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Subtotal calvarial vault reconstruction utilizing a customized polyetheretherketone (PEEK) implant with chimeric microvascular soft tissue coverage in a patient with syndrome of the trephined: A case report

Wang JS, Ter Louw R, DeFazio MV, McGrail KM, Evans KK

The syndrome of the trephined is a neurologic phenomenon that manifests as sudden decline in cognition, behavior, and sensorimotor function due to loss of intracranial domain. This scenario typically occurs...
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Diverse characters of Brennan’s paw incision model regarding certain parameters in the rat

Kumar R, Gupta S, Gautam M, Jhajhria S, Ray SB

BACKGROUND: Brennan’s rodent paw incision model has been extensively used for understanding mechanisms underlying postoperative pain in humans. However, alterations of physiological parameters like blood pressure and heart rate, or...
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Comparison of the immediate hemodynamic changes induced by unilateral and bilateral spinal anesthesia in hypertensive elderly patients

Cho WJ, Yun SH, Oh JH, Lee K, Kim HJ

BACKGROUND: The objective of this study was to compare the frequency of hypotension and immediate hemodynamic changes induced by unilateral and bilateral spinal anesthesia in hypertensive elderly patients. METHODS: Forty hypertensive...
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The change of stroke volume variation during thoracotomy or one lung ventilation

Lim H, Kim DC, Kim MJ, Yoo S, Ki MJ, Kang S, Kim D

BACKGROUND: Stroke volume variation (SVV) is based on cyclic changes of intrathoracic pressure during respiratory cycle. Thoracotomy and one-lung ventilation (OLV) can lead to changes in airway and intrathoracic pressure....
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Effects of fetal position on maternal hemodynamics after spinal anesthesia for cesarean delivery

Park YW, Lee IH

BACKGROUND: Aortocaval compression by the gravid uterus is a known physiological phenomenon that is classically claimed to cause supine hypotension in full-term pregnant women. This study aimed to investigate the...
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