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Propofol promotes osteoclastic bone resorption by increasing DC-STAMP expression

Kim EJ, Kim HJ, Baik SW, Kim KH, Ryu SJ, Kim CH, Shin SW

BACKGROUND: Propofol is an intravenous anesthetic which has antioxidant effects due to its similarity in molecular structure to α-tocopherol. It has been reported that α-tocopherol increases osteoclast fusion and bone...
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Post-operative intravenous patient-controlled analgesic efficacy of morphine with ketorolac versus nefopam after laparoscopic gynecologic surgery: a randomized non-inferiority trial

Yoon JU, Byeon GJ, Cheon JH, Choi YM, Ri HS, Baik SW

BACKGROUND: Nefopam is a non-opioid non-steroidal centrally acting analgesic. This study was conducted to assess the analgesic efficacy of intravenous patient-controlled analgesia (IV-PCA) using nefopam alone, compared with a combination...
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Foreign Body Removal at Right Main Bronchus in A Neonate

Ri HS, Shin SW, Baek SH, Kim HJ, Lee SJ, Baik SW

Foreign body in the airway could be a life-threatening risk, especially for young pediatric patients. A 6-day old male patient with foreign body, which was located deep in the right...
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Administration of four different doses of gabapentin reduces awakening from breakthrough pain and adverse effects in outpatients with neuropathic pain during the initial titration

Yang JY, Lee WI, Shin WK, Kim CH, Baik SW, Kim KH

BACKGROUND: Gabapentin is a safe and well-tolerated anticonvulsant with a wide therapeutic index, and it is used for neuropathic pain. The aim of this study was to compare previous dosing...
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Optimal dose of dexmedetomidine for sedation during spinal anesthesia

Ok HG, Baek SH, Baik SW, Kim HK, Shin SW, Kim KH

BACKGROUND: Sedation in spinal anesthesia can reduce patient's anxiety and discomfort. Dexmedetomidine has a sedative, hypnotic, analgesic, and minimal respiratory depression effect. However, use of the dexmedetomidine is associated with...
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The changes of mitochondrial cytochrome c and GABAergic neuron in neuropathic pain model

Kim WS, Park JY, Kim TK, Baik SW

BACKGROUND: Role of cytochrome c (Cyt c) is an apoptogenic agent under certain conditions. The mitochondrial permeability transition pore (MPTP) plays an important role in cell death since it opens,...
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Effects of etomidate on bispectral index scale and spectral entropy during induction of anesthesia by means of the raw electroencephalographic and electromyographic characteristics

Kim HM, Shin SW, Yoon JY, Lee HJ, Kim KH, Baik SW

BACKGROUND: Etomidate frequently induces myoclonus, so it may affect electromyographics (EMG). And EMG commonly has an effect on the bispectral index scale (BIS) and spectral entropy. This study was performed...
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The proper effect site concentration of remifentanil for prevention of myoclonus after etomidate injection

Ri HS, Shin SW, Kim TK, Baik SW, Yoon JU, Byeon GJ

BACKGROUND: Etomidate frequently induces myoclonus when administered intravenously with bolus injection during anesthetic induction. This can be bothersome for the anesthesiologist. The dose of remifentanil appropriate for preventing myoclonus without...
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Effect of the separated airway on the Intubating condition in fiberoptic bronchoscope-guided intubation fiberoptic intubation using separated airway

Kim JY, Do WS, Baek SH, Baik SW, Lee HJ

  • KMID: 1741925
  • Anesth Pain Med.
  • 2011 Jul;6(3):298-302.
BACKGROUND: Fiberoptic bronchoscope guided intubation is an important method of difficult airway management. The use of specific airways has been devised to assist the fiberoptic intubation. The authours compared effectiveness...
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Apoptosis of the GABAergic interneuron in the dorsal horn of the chronic post-ischemic pain model

Park JH, Kim TK, Kim HK, Baik SW

BACKGROUND: It is well known that the GABAergic inhibitory interneuronal system plays an important role in modulation of the noxious stimulation transmitted from the primary afferent input. Some studies have...
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Effects of sevoflurane on wound healing process

Cha MS, Lee HJ, Bae JH, Yang WS, Baik SW

BACKGROUND: Wound healing process is a tissue response to trauma which leads to tissue repair through complex biological stages. Sevoflurane is a widely used inhalation anesthetic for surgery, but there...
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Effect of thromboembolic deterrent stockings at spinal anesthesia-induced hypotension

Kim WS, Baik SW, Kim HJ, Yoon JY, Lee HJ, Kim TK

BACKGROUND: Hypotension during spinal anesthesia is mainly result of sympathetic blockade, which causes pooling of blood into the lower extremities. Mechanical compression of lower limbs prevents venous pooling of blood....
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The Antiallodynic Effect and the Change of the alpha2 Adrenergic Receptor Subtype mRNA Expression by Morphine Administration in a Spinal Nerve Ligation Rat Model

Chung KY, Shin SW, Kwon SA, Kim TK, Baek SH, Baik SW

BACKGROUND: The neuropathic pain arising from nerve injury is difficult to treat and the therapeutic effects of opioid drugs remain debatable. Agonists acting at the alpha2 adrenergic and opioid receptors...
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Effects of Propofol on Arginine Vasopressin-induced Contraction in Isolated Human Gastroepiploic Artery

Lee SJ, Baik SW, Cho HR, Kim WS, Baek SH

BACKGROUND: Arginine vasopressin has been used by prophylactic treatment of vasodilatory shock during coronary artery bypass graft (CABG). Vasopressin may be a cause of spasm in graft artery during CABG....
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Assessing the Effectiveness of Medical Ethics Education

Kim SS, Park BK, Chang CL, Kim HK, Kang SY, Baik SW

  • KMID: 2306703
  • Korean J Med Educ.
  • 2008 Mar;20(1):73-82.
PURPOSE: The purpose of this study is to evaluate the effectiveness of a medical ethics course taught in medical school by examining the students' abilities to identify medical ethics issues,...
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The Effect of Remifentanil on Delirium after Sevoflurane Anesthesia in the Pediatric Patients

Kim HJ, Baik SW, Baek SH, Kim HK

BACKGROUND: Sevoflurane is commonly used anesthetics for pediatric surgical patients. Emergence delirium is more frequent when recovering from sevoflurane anesthesia than other anesthetics. In this study, we evaluated the effect...
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Sevoflurane Does not Adversely Affect Myocardial Function after Ventricular Septal Defect Repair in Children

Baek SH, Kwon JY, Baik SW, Kim HK, Kim SM

BACKGROUND: Myocardial dysfunction after cardiopulmonary bypass (CPB) is a significant cause of morbidity and mortality after congenital cardiac surgery. The aim of this study was to evaluate myocardial function on...
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The Change of Neuropathic Pain and Pain Related Gene Expression following Exposure to Chronic Smoking

Lee HJ, Shin SW, Yang WS, Baek SH, Kim CH, Kim HK, Baik SW

BACKGROUND: Several studies have reported reduced pain and anxiety in smokers, and considerable evidence shows that smoking induces analgesia, which is thought to be nicotine-mediated. We investigated if smoking could...
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The Changes of Differences of Pulse Transit Time between Toe and Finger in General and Epidural Anesthesia

Kim TK, Cho AR, Choi BC, Baik SW

BACKGROUND: Pulse wave velocity (PWV) and pulse transit time (PTT) are influenced by the arterial wall stiffness and compliance. Also, the PTT is dependent on blood pressure changes that can...
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Airway Management of a Pediatric Patient with Interarytenoid Adhesion : A case report

Shin CS, Kwon JY, Baik SW, Kim HK

  • KMID: 1917407
  • Anesth Pain Med.
  • 2007 Apr;2(2):78-81.
Interarytenoid adhesion is a rare complication associated with endotracheal intubation. The vocal cord is fixed to arytenoid cartilage and the movement of vocal cord is limited. Its clinical symptoms are...
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