Korean Circ J.  1984 Jun;14(1):1-6. 10.4070/kcj.1984.14.1.1.

Isovolumic Phase Indices of Myocardial Contractility in 16 Korean Adults with Normal Physical Activities

• Park SW
• Han DS
• Kim JH
• Park CH
• Lee MM
• Park YB
• Choi YS
• Seo JD
• Lee YW

• KMID: 2229806
• DOI: http://doi.org/10.4070/kcj.1984.14.1.1

Abstract

Assessment of Myocardial contractility is critically important task in the evaluation of patients with heart disease. In recent years many indices have been studied to evaluate myocardial inotropic state, applying the skeletal muscle mechanics to intact heart. Among such indices, Vmax(maximum velocity of shortening of the unloaded contractile elements) and Vpm(physiologic maximum observed velocity of myocardial shortening) provide a measure of myocardial contractility independent of preload or afterload. To obtain normal values in Korean adults, the left ventricular pressure data of 16 patients with normal physical activities were analyzed, using the digital computer. Seven patients had ventricular septal defect with Qp/Qs less than 2.0, one patient had mitral stenosis, another one patient had mitral stenosis and aortic regurgitation (grade I/IV and the remainder seven patients had no intrinsic cardiac disorder. But, the cardiac performances of all patients were apparently normal. The results were as follows: 1) Cardiac index was greater than 3.0 l/min/m2 in all patinets: 4.9+/-1.32(+/-S.D.)l.min/m2. 2) Ejection fraction was greater than 55% in all patients: 71.2+/-8.04(+/-S.D.)%. 3) Left ventricular end diastolic pressure(LVEDP) ranged from 3 mmHg to 12 mmHg. 4) Vmax: 48.1+/-9.41(+/-S.D.) sec(-1). 5) Vpm: 39.3+/-8.13(+/-S.D.) sec(-1).

MeSH Terms

Adult*
Aortic Valve Insufficiency
Computers
Heart
Heart Diseases
Heart Septal Defects, Ventricular
Humans
Mechanics
Mitral Valve Stenosis
Motor Activity*
Muscle, Skeletal
Reference Values
Ventricular Pressure