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Toxicity Profile of Temozolomide in the Treatment of 300 Malignant Glioma Patients in Korea

Bae SH, Park MJ, Lee MM, Kim TM, Lee SH, Cho SY, Kim YH, Kim YJ, Park CK, Kim CY

This study evaluated the toxicity profiles of temozolomide in the treatment of malignant glioma as either concurrent or adjuvant chemotherapy. We retrospectively reviewed the medical records of 300 malignant glioma...
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Primary leiomyoma of the ovaries in a dog

Lee HW, Kang KK, Min CW, Kim AY, Lee EM, Lee EJ, Lee MM, Kim SH, Sung SE, Jeong KS

  • KMID: 2168991
  • J Biomed Res.
  • 2014 Mar;15(1):53-56.
We would like to report a case of leiomyoma of the ovaries in a dog. Leiomyoma is commonly seen in the vagina in dogs. However, it is a very rare...
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High Sodium Intake in Women with Metabolic Syndrome

Rhee MY, Kim JH, Kim YS, Chung JW, Bae JH, Nah DY, Kim YK, Lee MM, Lim CY, Byun JE, Park HK, Kang BW, Kim JW, Kim SW

BACKGROUND AND OBJECTIVES: Metabolic syndrome and high sodium intake are associated with frequent cardiovascular events. Few studies have estimated sodium intake in subjects with metabolic syndrome by 24-hour urine sodium...
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Case of Sporadic T-cell Lymphosarcoma in Cattle

Yang JY, Jeong DH, Min CW, Kang KK, Kim AY, Lee EM, Lee EJ, Lee MM, Kim SH, Sung SE, Jeong KS

  • KMID: 2055105
  • J Biomed Res.
  • 2013 Sep;14(3):177-179.
We would like to report a case of bovine lymphosarcoma. Parous cattle from a livestock farmhouse were examined for mutinodular masses in the abdominal cavity after slaughter. For clinical signs,...
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A case of metastatic cholangiocarcinoma in a ferret

Lee HS, Kang KK, Min CW, Kim AY, Lee EM, Lee EJ, Lee MM, Kim SH, Sung SE, Jeong KS

  • KMID: 1498933
  • J Biomed Res.
  • 2013 Jun;14(2):128-131.
Cholangiocarcinoma is a relatively rare neoplasm in animals and humans. A four-year-old, neutered male ferret presented with depression, anorexia, cachexia, diarrhea, and icterus. Necropsy findings included ascites, multiple white nodules...
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Emotional Response of ICU Patients Family toward Physical Restraints

Kang J, Lee EN, Park EY, Lee Y, Lee MM

  • KMID: 2298267
  • Korean J Adult Nurs.
  • 2013 Apr;25(2):148-156.
PURPOSE: The purpose of this study was to investigate the emotional response of family members of physically restrained patients in the intensive care units (ICUs). METHODS: The study subjects were 200...
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Subclinical Renal Insufficiency Range of Estimated Glomerular Filtration Rate and Microalbuminuria Are Independently Associated with Increased Arterial Stiffness in Never Treated Hypertensives

Nah DY, Lee CG, Bae JH, Chung JW, Rhee MY, Kim JH, Kim YS, Kim YK, Lee MM

BACKGROUND AND OBJECTIVES: Microalbuminuria (MAU) and decreased estimated glomerular filtration rate (eGFR) are risk factors for cardiovascular disease (CVD) in patients with hypertension. However, in hypertensive patients with normal or...
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Chronic pyometra due to bilateral ovarian tumors in a South American sea lion

Yang H, Do SH, Lee EM, Kim AY, Lee EJ, Min CW, Kang KK, Lee MM, Jeong KS

  • KMID: 2055096
  • J Biomed Res.
  • 2013 Mar;14(1):47-50.
A 14-year-old female South American sea lion (Otaria byronia) with persistent vaginal secretion and chronic hemorrhagic diarrhea was encountered. During postmortem examination, the uterus was found to resemble a balloon...
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The Prognostic Implication of Metabolic Syndrome in Patients with Heart Failure

Yoon HJ, Ahn Y, Kim KH, Park JC, Choi DJ, Han S, Jeon ES, Cho MC, Kim JJ, Yoo BS, Shin MS, Seong IW, Kang SM, Kim YJ, Kim HS, Chae SC, Oh BH, Lee MM, Ryu KH, The Korea HF Registry

BACKGROUND AND OBJECTIVES: Metabolic syndrome (MetS) increases the risk of heart failure (HF). The purpose of this study was to identify the prevalence of MetS in patients with HF and...
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Characteristics, Outcomes and Predictors of Long-Term Mortality for Patients Hospitalized for Acute Heart Failure: A Report From the Korean Heart Failure Registry

Choi DJ, Han S, Jeon ES, Cho MC, Kim JJ, Yoo BS, Shin MS, Seong IW, Ahn Y, Kang SM, Kim YJ, Kim HS, Chae SC, Oh BH, Lee MM, Ryu KH, KorHF Registry

BACKGROUND AND OBJECTIVES: Acute heart failure (AHF) is associated with a poor prognosis and it requires repeated hospitalizations. However, there are few studies on the characteristics, treatment and prognostic factors...
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Relationship Between Serum Uric Acid Levels, Metabolic Syndrome, and Arterial Stiffness in Korean

Lim JH, Kim YK, Kim YS, Na SH, Rhee MY, Lee MM

BACKGROUND AND OBJECTIVES: Associations have been reported between the serum uric acid (SUA) level, metabolic syndrome (MS), and atherosclerosis. We have determined the relationship between the SUA level, MS, and...
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Telmisartan Versus Carvedilol in Hypertensive Patients with Metabolic Syndrome: Effects on Blood Pressure, Arterial Stiffness, Blood Glucose, and Lipid Metabolism

Kim YS, Kim SY, Bae JH, Nah DY, Rhee MY, Lee MM, Huh HJ, Chae SL, Kim YK

  • KMID: 1750379
  • J Korean Soc Hypertens.
  • 2010 Dec;16(4):44-53.
BACKGROUND: We compared the effects of telmisartan and carvedilol on blood pressure (BP), aortic stiffness, glucose, and lipid metabolism in hypertensive patients with metabolic syndrome (MS). METHODS: A total of 26...
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Effects of Physical Activity and Aerobic Exercise Capacity on Aortic Stiffness in Patients With Untreated Hypertension

Na SH, Kim YS, Bae JH, Nah DY, Kim YK, Lee MM, Kim HY, Rhee MY

BACKGROUND AND OBJECTIVES: High aerobic exercise capacity and sport-related physical activity are reported to be inversely associated with arterial stiffness in healthy young adults. However, it is unknown whether increased...
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The Outcomes of Concomitant Chemoradiotherapy Followed by Adjuvant Chemotherapy with Temozolomide for Newly Diagnosed High Grade Gliomas : The Preliminary Results of Single Center Prospective Study

Choi JW, Lee MM, Kim IA, Kim JH, Choe G, Kim CY

OBJECTIVE: Malignant gliomas are the most common primary cerebral neoplasms in adults. Despite multimodality treatments, the prognosis for patients with malignant glioma remains poor. However, recently, the effectiveness of concomitant...
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Late Late Stent Thrombosis after Intracoronary Brachytherapy: Learning from Brachytherapy Experiences in the Drug-Eluting Stent Era

Shin DH, Kwon DA, Chung JW, Lee SP, Chang SA, Kang BS, Park KW, Kang HJ, Koo BK, Chae IH, Kim HS, Sohn DW, Oh BH, Lee MM, Park YB, Choi YS

Stent thrombosis is generally a fatal complication after percutaneous coronary intervention. Combined antiplatelet therapy is recommended to prevent stent thrombosis in those patients who have undergone stenting. However, there are...
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Increased Arterial Stiffness in Behcet's Disease Patients

Rhee MY, Na SH, Kim YK, Lee MM, Kim SK, Kim W

BACKGROUND AND OBJECTIVES : Pulse wave velocity (PWV) is an ideal indicator of arterial stiffness. This study investigated arterial stiffness of different vascular regions in patients suffering with Behcet's disease...
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Morphologic Follow-Up of the Anastomotic Sites Using One-year and Five-year Angiography after Coronary Artery Bypass Grafting

Cho KR, Kim KB, Kim JS, Choi JS, Chae IH, Oh BH, Lee MM, Park YB

  • KMID: 1885841
  • Korean J Thorac Cardiovasc Surg.
  • 2005 Mar;38(3):191-196.
BACKGROUND: We analysed the characteristics of anastomotic sites after coronary artery bypass grafting (CABG) using coronary angiographies (CAGs) performed at one and five years postoperatively in the same patient population....
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NF-kappa B decoy potentiates the effects of radiation on vascular smooth muscle cells by enhancing apoptosis

Zhang SY, Park KW, Oh S, Cho HJ, Cho HJ, Park JS, Cho YS, Koo BK, Chae IH, Choi DJ, Kim HS, Lee MM

  • KMID: 1033097
  • Exp Mol Med.
  • 2005 Feb;37(1):18-26.
NF-kappa B promotes cell survival against external stress such as radiation. We examined whether NF-kappa B decoy transfection enhances the antiproliferative effects of radiation on vascular smooth muscle cells (VSMCs)...
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Association of the Invasively Measured Aortic Stiffness and Coronary Artery Disease

Park JS, Seo JJ, Chung JW, Cho HJ, Bae JW, Kim KI, Kang HJ, Koo BK, Yeon TJ, Kim YJ, Kim HS, Sohn DW, Lee MM, Park YB, Choi YS, Oh BH

BACKGROUND AND OBJECTIVES: Aortic stiffness is believed to be an important risk factor of coronary artery atherosclerosis (CAA), as it directly affects coronary perfusion. The following aspects of the invasively...
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Risk Factors of No-Reflow Phenomenon after Primary Percutaneous Coronary Intervention with Stent Implantation

Park JS, Bae JW, Koo BK, Yeon TJ, Kim HS, Sohn DW, Oh BH, Park YB, Choi YS, Chae IH, Choi DJ, Choi D, Jang Y, Shim WH, Cho SY, Kim K, Kim D, Cho M, Lee MM

BACKGROUND AND OBJECTIVES: No-reflow is an important phenomenon for limiting the prognosis of patients following primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). Coronary stenting is the current...
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