Korean Circ J.  2008 Mar;38(3):131-134. 10.4070/kcj.2008.38.3.131.

Blood Pressure Variation and Cardiovascular Risks

  • 1Cardiology Division, Yongdong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. sejoong@yumc.yonsei.ac.kr


There are short-term and long-term variations seen in blood pressure. An abnormal pattern in cyclic variations of blood pressure (diurnal or seasonal) correlates well with an increased cardiovascular risk for hypertension, regardless of the resting blood pressure level. Increased blood pressure reactivity to external stimuli is also associated with a higher cardiovascular risk, and may be a significant determinant of cyclic blood pressure variations. A further understanding of the pathophysiological basis of abnormal blood pressure variations is recommended, and the physiological factors should be considered as new therapeutic targets.


Blood pressure; Circadian rhythm; Seasonal variation; Prognosis

MeSH Terms

Blood Pressure
Circadian Rhythm


  • Fig. 1 An integrated model of blood pressure variation and cardiovascular risk. The addition of exaggerated blood pressure variation to resting hypertension leads to high-risk hypertension. BP: blood pressure.


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