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Peptides derived from high voltage-gated calcium channel ββ subunit reduce blood pressure in rats

Kim HK, Jun J, Kim TW, Youn Dh

The β subunits of high voltage-gated calcium channels (HGCCs) are essential for optimal channel functions such as channel gating, activation-inactivation kinetics, and trafficking to the membrane. In this study, we...
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Educational Program with Text Messaging for Community-Dwelling Patients with Hypertension: A Pilot Randomized Controlled Trial

Tam HL, Wong EML, Cheung K

Purpose Controlling blood pressure minimizes the risk of cardiovascular events among patients with hypertension. Despite regular follow-ups, the hypertension management for patients aged ≥45 years is limited as evidenced from a...
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Prognostic Significance of 24-Hour Ambulatory Blood Pressure and Holter Monitoring in Patients without Atrial Fibrillation

Park S, Park J, Choi Y, Shin S, Park J

Objectives: This study investigated the 24-hour ambulatory blood pressure monitoring (ABPM) and Holter parameters for evaluating their prognostic significance of cardiovascular events including stroke in population without atrial fibrillation (AF). Methods:...
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The Association Between On-treatment Ambulatory Central Blood Pressure and Left Ventricular Reverse Remodeling in Heart Failure With Reduced Ejection Fraction

Ha J, Lee CJ, Oh J, Park S, Lee SH, Kang SM

Background and Objectives: Compared to office blood pressure (OBP), central blood pressure (CBP) and ambulatory blood pressure (BP) are known to be better markers for predicting cardiovascular events. We evaluated...
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Association between the Urine Cotinine Level and Blood Pressure in Korean Adults with Secondhand Smoke Exposure: Korea National Health and Nutritional Examination Survey 2016–2018

Lee JH, Shim JY, Lee JW

Background: Similar to smoking, exposure to secondhand smoke is a risk factor for developing hypertension and cardiovascular diseases; however, there is no standardized method for measuring smoke exposure. Measuring urine...
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Optimal target blood pressure in older patients with hypertension

Kim Ki

Hypertension is a common condition among older adults, and blood pressure (BP) control is effective for preventing cardiovascular morbidity and mortality even among the oldest-old adults. However, the optimal target...
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The Influence of Systolic Blood Pressure at the Time of Extubation on the Development of Postoperative Spinal Epidural Hematoma

Ahn DK, Kim YH, Ko YR, Jang SJ, Jung JS

Background: The most common cause of neurological complications after a biportal endoscopic spine surgery (BESS) is postoperative spinal epidural hematomas (POSEH). The objective of this study was to determine the...
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The effect of curcumin on blood pressure and cognitive impairment in spontaneously hypertensive rats

Lim JY, Kim W, Ha AW

BACKGROUND/OBJECTIVES: It is known that the renin-angiotensin system (RAS) in the brain could regulate cognitive functions as well as blood pressure. Inhibition of RAS for the improvement of cognitive function...
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Association between DIO2 Thr92Ala polymorphism and hypertension in patients with hypothyroidism: Korean Genome and Epidemiology Study

Kang YM, Koo BS, Yi HS, Kim JT, Park B, Lee JH, Shong M, Kang YE

Background/Aims: Recent evidence has identified the significance of type 2 iodothyronine deiodinase (DIO2) in various diseases. However, the role of DIO2 polymorphism in metabolic parameters in patients with hypothyroidism is...
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Intensified Multifactorial Intervention in Patients with Type 2 Diabetes Mellitus

Sasako T, Yamauchi T, Ueki K

In the management of diabetes mellitus, one of the most important goals is to prevent its micro- and macrovascular complications, and to that end, multifactorial intervention is widely recommended. Intensified...
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Predictive Value of Exercise Blood Pressure Changes for Orthostatic Hypotension in Patients With Parkinson’s Disease

Qin Y, Jin Zh, Zhang Zy, Chen Kk, Yu X, Yan Hj, Wang Rd, Su Y, Liu Ax, Xi Jn, Fang By

Background and Purpose Orthostatic hypotension (OH) is common in patients with Parkinson’s disease (PD). Early recognition OH is required with sensitive assessments. The purpose of this study was to determine...
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Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort

Lee JY, Bak JK, Kim M, Shin HG, Park KI, Lee SP, Lee HS, Lee JY, Kim Ki, Kang SH, Lee JH, Jang SY, Lee JH, Kim KH, Cho JY, Park JH, Park SK, Lee HY

Background/Aims: This study evaluated the long-term cardiovascular complications among Korean patients with hypertension and compared them with that of controls without hypertension. Methods: The Korean Hypertension Cohort (KHC) enrolled 11,043 patients...
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Association of blood pressure measurements in sitting, supine, and standing positions with the 10-year risk of mortality in Korean adults

Baik I, Kim NH, Kim SH, Shin C

OBJECTIVES: This prospective cohort study investigated the association between blood pressure (BP) as measured in different body postures and all-cause and cardiovascular (CV) mortality risk. METHODS: This population-based investigation included 8,901...
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The 2022 focused update of the 2018 Korean Hypertension Society Guidelines for the management of hypertension

Kim H, Lee E, Ahn S, Kim K, Kim H, Kim J, Lee H, Lee J, Park J, Cho E, Park S, Shin J, Kim Y

Hypertension is the leading cause of death in human being, which shows high prevalence and associated complica‑ tions that increase the mortality and morbidity. Controlling blood pressure (BP) is very...
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The association between carbon and nitrogen stable isotope ratios of human hair and hypertension

Ahn S, Park J

Background: The relationship between stable isotope ratios and dietary protein sources has been reported. How‑ ever, few studies have examined the effect of stable isotope ratios on metabolic risk in...
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Role of home blood pressure monitoring in resistant hypertension

Kim HM, Shin J

The definition of resistant hypertension (RHT) has been updated to include failure to achieve target blood pressure (BP) despite treatment with ≥3 antihypertensive drugs, including diuretics, renin-angiotensin system blockers, and...
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Relationships among Handgrip Strength, Blood Pressure, Dialysis Adequacy, Dialysis Symptoms, and Depression in Hemodialysis Patients

Kim CH, Moon SS

Purpose: This study aimed to determine relationships among handgrip strength (HGS), blood pressure, dialysis adequacy, dialysis symptoms, and depression in hemodialysis patients. Methods: Data from 150 subjects were obtained and...
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Hypertensive crisis following mRNA COVID-19 vaccination in adolescents: two case reports

Cho MH, Cheong HI

In response to the global coronavirus disease 2019 (COVID-19) pandemic, vaccines were developed and approved quickly. However, numerous cardiovascular adverse events have been reported. We present two adolescent cases who...
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Is there a characteristic pattern of ambulatory blood pressure profile in type 1 diabetic children and adolescents?

Morić BV, Šamija I, Sabolić LLG, Stipančić G

Purpose: To examine the characteristics of ambulatory blood pressure (ABP) including blood pressure variability (BPV) and its association with albuminuria in type 1 diabetic (T1D) children and to identify potential...
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Is the immediate blood pressure control using parenteral antihypertensive drug needed for patients with severe high blood pressure with epistaxis in the emergency department?

Shin K, Park K, Lee H, Kim C, Kim LS, Yoo JW

  • KMID: 2535905
  • J Korean Soc Emerg Med.
  • 2022 Oct;33(5):471-479.
Objective: This study aimed to assess whether the conventional treatments administered in the emergency department (ED) for hypertensive urgencies (observed or peroral [PO]-controlled) in severe high blood pressure (BP) patients...
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