J Korean Ophthalmol Soc.  2015 Nov;56(11):1736-1741. 10.3341/jkos.2015.56.11.1736.

Lamina Cribrosa Thickness in the Fellow Eyes of Patients with Unilateral Retinal Vein Occlusion

• Kim YI
• Lee TY
• Lee KW
• Kim JS

• KMID: 2214182
• DOI: http://doi.org/10.3341/jkos.2015.56.11.1736

Abstract

PURPOSE
To compare the lamina cribrosa thickness in fellow eyes of patients with unilateral retinal vein occlusion (RVO) with the normal control eyes and the type of RVO.
METHODS
This study included 40 patients with unilateral RVO and 45 normal control subjects. We compared the lamina cribrosa thickness between the RVO eyes and the fellow eyes, the fellow eyes and the normal control eyes and the type of RVO eyes. We measured central lamina thickness using enhanced depth imaging spectral-domain optical coherence tomography.
RESULTS
In patients with unilateral RVO, central lamina cribrosa thickness was not significantly different between the RVO eyes (211.33 microm) and the fellow eyes (204.13 microm; p = 0.202). However, central lamina cribrosa thickness in the fellow eyes was significantly reduced compared with the normal control eyes (217.76 microm; p = 0.046). Central lamina cribrosa thickness in the fellow eyes according to the type of RVO was not statistically significantly different (p = 0.672).
CONCLUSIONS
This study showed that the central lamina cribrosa thickness in the fellow eyes of patients with unilateral RVO was thinner than in normal patients. Therefore, the lamina cribrosa thickness may be associated with RVO as well as glaucoma.

Keyword

Arteriovenous crossing retinal vein occlusion; Glaucoma; Lamina cribrosa thickness; Optic nerve-sited retinal vein occlusion; Retinal vein occlusion

MeSH Terms

Glaucoma
Humans
Retinal Vein Occlusion*
Retinal Vein*
Retinaldehyde*
Tomography, Optical Coherence
Retinaldehyde

Figure

• 

  Figure 1. Cross-sectional image of the optic nerve head by Spectralis® OCT in the EDI mode. The central lamina cribrosa thickness was measured between the anterior and posterior border of the highly reflective region that was visible beneath the center of optic disc cup (arrowheads). OCT = optical coherence tomography; EDI = enhanced depth imaging.

Reference

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