J Korean Ophthalmol Soc.  2016 Feb;57(2):264-275. 10.3341/jkos.2016.57.2.264.

Analysis of Macular Layer Thickness Measured Using Spectral Domain Optical Coherence Tomography in Korean Subjects

• Kim CH
• Jin SY
• Lee YH
• Chang YS

• KMID: 2213668
• DOI: http://doi.org/10.3341/jkos.2016.57.2.264

Abstract

PURPOSE
To analyze macular layer thickness using spectral domain optical coherence tomography (SD-OCT) in normal subjects.
METHODS
One hundred normal eyes were enrolled in this study. Macular thickness was measured via enhanced depth imaging using Heidelberg Spectralis(R) OCT, using calipers within the program.
RESULTS
Central subfield thickness was 11.35 +/- 2.11 microm in the retinal nerve fiber layer, 13.33 +/- 4.16 microm in the ganglion cell layer, 19.38 +/- 3.20 microm in the inner plexiform layer, 18.23 +/- 4.66 microm in the inner nuclear layer, 23.27+/- 6.83 microm in the outer plexiform layer, 91.97 +/- 9.59 microm in the outer nuclear layer, 16.68 +/- 1.83 microm in the retinal pigment epithelium layer, 179.82 +/- 29.99 microm in the inner retinal layer, and 88.32 +/- 2.81 microm in the photoreceptors layer. No significant differences were observed in the spherical equivalent according to age. Despite no significant differences being present, the macular central subfield thickness was thinner in women than in men.
CONCLUSIONS
In the present study, differences in macular layer thickness were found according to age and gender which should be considered when macular diseases are evaluated.

Keyword

Korean normal subjects; Macular layer thickness; Spectral domain optical coherence tomography

MeSH Terms

Female
Ganglion Cysts
Humans
Male
Nerve Fibers
Retinal Pigment Epithelium
Retinaldehyde
Tomography, Optical Coherence*
Retinaldehyde

Figure

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  Figure 1. ETDRS subfields within standard 1-, 3-, and 6-mm di-ameter concentric circles at the right used for reporting retinal thickness (central circle: F, inner ring: SI+NI+II+TI, outer ring: SO+NO+IO+TO). ETDRS = Early Treatment of Diabetic Retinopathy Study; F = fovea; SI = superior inner; NI = nasal inner; II = inferior inner; TI = temporal inner; SO = superior outer; NO = nasal outer; IO = inferior outer; TO = temporal outer.

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