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Serial Long-Term Growth and Neurodevelopment of Very-Low-BirthWeight Infants: 2022 Update on the Korean Neonatal Network

Jeon GW, Lee JH, Oh M, Chang YS

Background: We aimed to evaluate the long-term growth and neurodevelopmental outcomes of very-low-birth-weight infants (VLBWIs, birth weight < 1,500 g) born between 2013, the establishment of the Korean Neonatal Network...
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Serial Short-Term Outcomes of VeryLow-Birth-Weight Infants in the Korean Neonatal Network From 2013 to 2020

Jeon GW, Lee JH, Oh M, Chang YS

Background: We aimed to determine the current survival rate and short-term outcomes of very-low-birth-weight infants (VLBWIs) in Korea, as well as whether the survival rate and short-term outcomes have improved...
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Cytokine Inductions and Intracellular Signal Profiles by Stimulation of dsRNA and SEB in the Macrophages and Epithelial Cells

Choi JP, Losol P, Ayoub G, Ji M, Kim SH, Cho SH, Chang YS

Foreign molecules, including viruses and bacteria-derived toxins, can also induce airway inflammation. However, to the best of our knowledge, the roles of these molecules in the development of airway inflammation...
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Perinatal Outcomes According to Accessibility to Maternal-Fetal and Neonatal Intensive Care Units by Region in Korea

Lee JH, Kwon HS, Noh YM, Shin H, Kim T, Lee TH, Chang YS

Background: Herein, we aimed to evaluate the maternal mortality ratio and perinatal mortality rate for different perinatal medical care service areas (PMCSAs), which were established by considering their geographical accessibility...
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ABT-737, a BH3 Mimetic, Enhances the Therapeutic Effects of Ionizing Radiation in K-ras Mutant Non-Small Cell Lung Cancer Preclinical Model

Lee JM, Kim HS, Kim A, Chang YS, Lee JG, Cho J, Kim EY

Purpose: Tumor radioresistance and dose-limiting toxicity restrict the curative potential of radiotherapy, requiring novel approaches to overcome the limitations and augment the efficacy. Here, we investigated the effects of signal...
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Association between soluble forms of the receptor for advanced glycation end products and periodontal disease: a retrospective study

Kim KS, Lee YJ, Ahn S, Chang YS, Choi Y, Lee HJ

Objectives: Periodontitis is the most common chronic disease that causes tooth loss and is related to systemic diseases such as cardiovascular dis- ease and diabetes. An objective indicator of the current...
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A case of anaphylaxis caused by exposure to walnuts

Lee H, Kim JH, Kim YH, Seo B, Kim SH, Chang YS

Anaphylaxis is an acute serious systemic allergic reaction that can lead to death, requiring immediate diagnosis and treatment. In particular, food is the most common cause in children, adolescents, and...
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Frequency and clinical characteristics of adverse transfusion reactions in hospitalized patients: A retrospective review of electronic medical records

Kim YH, Seo JH, Ahn KM, Yang MS, Kim SH, Cho SH, Chang YS

Purpose: Adverse transfusion reactions (ATRs) are unfavorable reactions to the transfused unit, and the severity may be different among individuals, depending upon the type of reactions and the patient’s susceptibility....
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Type 2 hereditary angioedema treated with acute exacerbation with icatibant: A case report

Hwang YK, An KM, Kim YH, Kim SH, Chang YS

Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by genetic deficiency or decreased function of C1-esterase inhibitor. It is characterized by swelling of subcutaneous and submucosal tissues of...
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The Role of Upper Airway Microbiome in the Development of Adult Asthma

Losol P, Choi JP, Kim SH, Chang YS

Clinical and molecular phenotypes of asthma are complex. The main phenotypes of adult asthma are characterized by eosinophil and/or neutrophil cell dominant airway inflammation that represent distinct clinical features. Upper...
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Guidelines for Safe Drug Use

Kim SH, Jung HK, Shin ES, Lee JS, Ryu YJ, Hong KS, Bang SM, Chang YS, Kim CK, Lee BW, Hong SJ, Kim CO, the Clinical Practice Guidelines Committee of the Korean Association of Internal Medicine

Background/Aims: In Korea, medications are available by prescription from a physician, or can be purchased over-the-counter (OTC) without a prescription. Education regarding both prescribed and OTC drugs is important to...
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Neonatal Diabetes Mellitus Due to KCNJ11 (KIR6.2) Mutation Successfully Treated with Sulfonylurea

Jang S, Yang M, Ahn SY, Sung SI, Chang YS, Park WS

Neonatal diabetes mellitus (NDM) is a rare disease that occurs at less than 6 months of age and is presumably caused by a mutation in the gene that affects pancreatic...
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Risk factor leading to complicated appendicitis: pelvic position of the appendix

Koh H, Yang H, Cho K, Jung YY, Chang YS, Kim DH, Kim MS

  • KMID: 2515963
  • J Korean Soc Emerg Med.
  • 2021 Apr;32(2):134-142.
Objective: Several factors contribute to the progression of complicated appendicitis (CA) in patients diagnosed with acute appendicitis. The goal of this study was to investigate whether the pelvic location of...
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Neonatal Outcomes according to the Latent Period from Membrane Rupture to Delivery among Extremely Preterm Infants Exposed to Preterm Premature Rupture of Membrane: a Nationwide Cohort Study

Park JH, Bae JG, Chang YS

Background: In accordance with the guidelines for the expectant management of women exposed to previable preterm premature rupture of membrane, we compared neonatal outcomes according to the latent period from...
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Mortality and Morbidities according to Time of Birth in Extremely Low Birth Weight Infants

Yang M, Ahn SY, Jo HS, Sung SI, Chang YS, Park WS, KNN

Background: Although the overall quality of high-risk neonatal care has improved recently, there is still concern about a difference in the quality of care when comparing off-hour births and regular-hour...
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Retinol-binding protein-4 was associated with sensitization to inhalant allergens in the elderly population

Kim BK, Song WJ, Seo B, Kim JY, Kim SH, Jang HC, Kim KW, Chang YS

Background/Aims: Recent evidence suggests an association between allergic sensitization and metabolic markers. However, this association has rarely been examined in the elderly. Retinol-binding protein-4 (RBP-4) is a recently identified adipokine...
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Biomarkers and diagnostic tools for lung cancer

Lee SH, Lee EH, Kim EY, Choi YJ, Cha YJ, Chang YS

Lung cancer is the leading cause of cancer-related deaths in developing to advanced countries worldwide. The incidence rate of lung cancer in Korea has been increasing steadily since 1997. Statistics...
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The effects of maternal body mass index and plurality on maternal and umbilical cord serum magnesium levels in preterm birth at less than 32 weeks of gestation

Choi YS, Hong JY, Hong JY, Kim YM, Sung JH, Choi SJ, Oh Sy, Roh CR, Kim HS, Sung SI, Ahn SY, Chang YS

Objective To evaluate the effects of maternal body mass index (BMI) and plurality on maternal and umbilical cord serum magnesium levels after antenatal magnesium sulfate treatment. Methods This was a retrospective...
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Laparoscopic Treatment of Colonic Intussusception Caused by Sigmoid Colon Cancer

Kwak HY, Kim MS, Park JW, Kim DH, Lee JH, Chang YS

Reports on the laparoscopic treatment for colonic intussusception are exceedingly rare. We report a case of colonic intussusception caused by sigmoid colon cancer which was treated with a laparoscopic approach....
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Sedation for Brain Magnetic Resonance Imaging in Preterm Infants: Using Propofol under Anesthesiologist Supervision

Han YS, Kim HH, Kim HS, Yang MS, Ahn SY, Sung SI, Chang YS, Park WS

Purpose: We aimed to compare two different sedation protocols for brain magnetic resonance imaging (MRI) in preterm infants. One protocol used chloral hydrate (CH) with monitoring conducted by non-anesthesiologists, and...
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