J Korean Ophthalmol Soc.  2010 Apr;51(4):516-523. 10.3341/jkos.2010.51.4.516.

The Results of Nation-Wide Registry of Age-related Macular Degeneration in Korea

• Park KH
• Song SJ
• Lee WK
• Yoon HS
• Koh HJ
• Kim CG
• Kim YY
• Kang SW
• Kim HK
• Lee BR
• Nam DH
• Lee PY
• Kim HS
• Kim HC
• Kim SY
• Kim IY
• Kim GS
• Huh K
• Oh JR
• Kim SD
• Lee SJ
• Kim YD
• Kim SH
• Lee TG
• Joe SW
• Lee DC
• Chang MH
• Kim SD
• Joe YW
• Bae SR
• Lee JE
• Oum BS
• Yoon IH
• Kwon SI
• Kang JH
• Kim JI
• Moon SW
• Yu HG
• Yoon YH
• Chang GY
• Lee SC
• Lee SJ
• Park TK
• Ohn YH
• Kwon OW
• Chang WH
• Yang YS
• Lee SJ
• Lee SY
• Kim CR
• Lee JH
• Moon YS
• Ahn JK
• Joe NC
• Choi GJ
• Joe YJ
• Kim SK
• Park SP
• Nam WH
• Joe HY
• Kim JH
• Chung H

• KMID: 2213394
• DOI: http://doi.org/10.3341/jkos.2010.51.4.516

Abstract

PURPOSE
To evaluate the incidence and clinical features of age-related macular degeneration (AMD) in Korea.
METHODS
Web-based (www.armd-nova.or.kr) registration was conducted for AMD patients aged 50 or more who were newly diagnosed by retinal specialists in Korea from August 20, 2005 to August 20, 2006. Patient data including ophthalmologic examination, fundus photography, fluorescein angiogram and/or indocyanin green angiogram (ICG), past medical history, behavioral habit, combined systemic diseases were up-loaded.
RESULTS
Among finally enrolled 1,141 newly diagnosed AMD patients, 690 patients (60.5%) were male and 451 patients (39.5%) were female. The average age of AMD patients was 69.7+/-8.0. Early AMD was observed in 190 patients and 951 patients had late AMD. Classic choroidal neovascular membrane (CNVM) was observed in 18.6% of exudative AMD patients and 63.4 % had occult CNVM. Subfoveal CNVM was observed in 80.4% of the patients with CNVM. Among the 580 exudative AMD eyes that performed indocyanin green angiography (ICG), 184 eyes (31.7%) had polypoidal choroidal vasculopathy (PCV) and 36 eyes (6.2%) showed retinal angiomatous proliferation (RAP). Age, male gender, smoking, diabetes and hypertension significantly increased the risk of the AMD among Koreans.
CONCLUSIONS
Because of the low rate of participation by retinal specialists, definite incidence of AMD was not obtainable. However, the estimated 1-year AMD incidence in the Pusan area of Korea is at least 0.4%. In contrast to Western people, 31.7% of exudative AMD cases were revealed to be PCV and 6.2% were revealed to be RAP. This discrepancy between ethnic groups should be considered in the diagnosis and treatment modality selection of Korean AMD patients.

Keyword

Age-related macular degeneration; Choroidal neovascular membrane; Korean; Polypoidal choroidal vasculopathy

MeSH Terms

Aged
Angiography
Choroid
Ethnic Groups
Eye
Female
Fluorescein
Humans
Hypertension
Incidence
Korea
Macular Degeneration
Male
Membranes
Photography
Retinaldehyde
Smoke
Smoking
Specialization
Fluorescein
Retinaldehyde
Smoke

Figure

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  Figure 1. Registry homepage (www.armd-nova.or.kr) of the Korean Retina Society for uploading the data of patients with age-related macular degeneration.

Reference

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