J Korean Ophthalmol Soc.  2002 Oct;43(10):1918-1927.

The Effect of Dopamine therapy on the Development of Retinopathy of Prematurity

• Kim WS
• Ahn SK
• Koo BS

Abstract

PURPOSE: Since a recent study that the use of dopamine therapy for the hypotension of premature infants was a risk factor on the development of retinopathy of prematurity was reported, this study was intended to access whether treatment of premature infants with dopamine acts as a risk factor for development of retinopathy of prematurity.
METHODS
We retrospectively reviewed the medical records of 123 premature infants who had been admitted in our Neonate Intensive Care Unit, and were alive and born under 36 weeks of gestational age, between January 1995 and December 1999. In comparing dopamine treated group (91) and non-treated group (31), we performed univariate and multivariate statiscal analysis for the comparisons of two groups.
RESULTS
Although in the incidence of retinopathy of prematurity, dopamine treated group (51 of 91,55.4%) was higher than non-treated group (15 of 31,48.4%), statistically, it was not significantly different(P< 0.05).
CONCLUSIONS
The use of dopamine therapy was not risk factor for the development of retinopathy of prematurity.

Keyword

Dopamine; Risk Factor; Retinopathy of prematurity

MeSH Terms

Dopamine*
Gestational Age
Humans
Hypotension
Incidence
Infant, Newborn
Infant, Premature
Intensive Care Units
Medical Records
Retinopathy of Prematurity*
Retrospective Studies
Risk Factors
Dopamine