J Korean Rheum Assoc.  1995 Jul;2(2):181-186.

A Case of Primary Sjiigren's Syndrome with Hypokalemic Paralysis and Renal Tubular Acidosis

  • 1Department of Internal Medicine, College of Medicine, Catholic University of Taegu-Hyosung, Taegu, Korea.


A 36-year old woman with Sjogren's syndrome, distal renal tubular acidosis and hypokalemic muscle paralysis is described. The main manifestation was muscle paralysis due to hypokalemia secondary to renal tubular acidosis. Review of English literatures revealed 13 cases of hypokalemic paralysis due to Sjogren's syndrome. The data from those reports have indicated that hypokalemic paralysis was seen more often in patients with primary Sjogren's syndrome than secondary one and that it might precede the classic sicca comple. Hypokalemic paralysis may serve as a clinical marker for more severe renal disease in patients who have primary Sjogren's syndrome and renal tubular acidosis, even though it is a rare manifestation of Sjogren's syndrome.


Hypokalemic paralysis; Renal tubular acidosis; Sjogren's syndrome
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