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A Pediatric Case of Long-term Untreated Distal Renal Tubular Acidosis

Kedsatha P, Shin HY, Choi Y, Cheong HI, Cho TJ, Yi E, Maisai M

Distal renal tubular acidosis (dRTA) is a rare renal tubular disorder characterized by normal anion gap metabolic acidosis, hypokalemia, and high urine pH. It can be inherited or acquired. In...
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Adult Idiopathic Renal Fanconi Syndrome: A Case Report

Park DJ, Jang KS, Kim GH

Renal Fanconi syndrome (RFS) is caused by generalized proximal tubular dysfunction and can be divided into hereditary and acquired form. Adult-onset RFS is usually associated with drug toxicity or systemic...
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Primary Autosomal Recessive Distal Renal Tubular Acidosis Caused by a Common Homozygous SLC4A1 Mutation in Two Lao Families

Park E, Phaymany V, Yi ES, Phangmanixay S, Cheong HI, Choi Y

Primary distal renal tubular acidosis (dRTA) caused by mutations of the SLC4A1 gene, which encodes for erythroid and kidney isoforms of anion exchanger, shows marked difference in inheritance patterns and...
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Renal Tubular Acidosis in Patients with Primary Sjögren's Syndrome

Jung SW, Park EJ, Kim JS, Lee TW, Ihm CG, Lee SH, Moon JY, Kim YG, Jeong KH

Primary Sjögren's syndrome (pSS) is characterized by lymphocytic infiltration of the exocrine glands resulting in decreased saliva and tear production. It uncommonly involves the kidneys in various forms, including tubulointerstitial...
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A Case of Distal Renal Tubular Acidosis with Sjögren's Syndrome Presenting as Hypokalemic Paralysis

Park HY, Seo JB, Hwang IR, Lee YR, Kim GY, Nam EJ, Kim JG

Distal renal tubular acidosis (RTA) caused by autoimmune nephritis occurs in up to 25% of patients with Sjögren's syndrome. However, patients with hypokalemic paralysis are sometimes overlooked, because most symptoms...
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Refractory rickets caused by mild distal renal tubular acidosis

Lee JH, Park JH, Ha TS, Han HS

Type I (distal) renal tubular acidosis (RTA) is a disorder associated with the failure to excrete hydrogen ions from the distal renal tubule. It is characterized by hyperchloremic metabolic acidosis,...
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A Case of Renal Tubular Acidosis Associated With Graves' Disease

Sim EH, Shin YS, Park MG, Yeo CW, Kang JD, Youn SO, Lee KJ

Renal tubular acidosis (RTA) is a metabolic acidosis caused by impaired excretion of hydrogen ions or reabsorption of bicarbonate. Disorders caused by impairment of bicarbonate reabsorption in the proximal tubule...
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Distal Renal Tubular Acidosis with Nephrocalcinosis in a Patient with Primary Sjogren's Syndrome

Lee JW, Lee BH, Lee MH, Oh SK, Seo JY, Kim HJ, Lee CW

Renal involvement is not uncommon in primary Sjogren's syndrome; however, it is clinically insignificant in most cases. Distal renal tubular acidosis accounts particularly for the majority. While the underlying distal...
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A Pediatric Case of Primary Sjogren's Syndrome Associated with Nephrogenic Diabetes Insipidus and Renal Tubular Acidosis

Choi JW, Jung YJ, Suh JS, Park SH, Koh DK

  • KMID: 2322037
  • J Korean Soc Pediatr Nephrol.
  • 2012 Oct;16(2):126-131.
Sjogren's syndrome (SS) is an autoimmune disorder primarily affecting the salivary and lacrimal glands. In addition, extra-glandular manifestations involving the lungs, liver, kidneys, pancreas, skin and central nervous system were...
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A Case of Type 1 Renal Tubular Acidosis and Osteomalacia in a Patient with Sjogren's Syndrome

Lee HJ, Lee SJ, Park SC, Park DJ, Kim TJ, Lee SS, Park YW

Sjogren's syndrome is a chronic autoimmune disease characterized by decreased function of the lacrimal and salivary glands. In addition, many other organs can be involved in patients with Sjogren's syndrome....
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Incomplete Distal Renal Tubular Acidosis with Nephrocalcinosis

Choi JS, Kim CS, Park JW, Bae EH, Ma SK, Kim SW

We report the case of a female patient with incomplete distal renal tubular acidosis with nephrocalcinosis. She was admitted to the hospital because of acute pyelonephritis. Imaging studies showed dual...
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Renal Expression of Ammonia Transporters in Rats with Amiloride-Induced Renal Tubular Acidosis

Kim SJ, Kim HY, Choi JH, Kim JT, Kim JE, Yeon MH, Kim SM, Kwon SK, Shin KS

  • KMID: 2259292
  • Korean J Med.
  • 2011 Jun;80(6):687-696.
BACKGROUND/AIMS: Renal tubular acidosis (RTA) decreases the net acid excretion, predominantly due to a decrease in urinary ammonia excretion. This study examined whether this decrement is associated with changes in...
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A Case of Cyclosporine-Induced Type I Renal Tubular Acidosis after Kidney Transplantation

Son SY, Lee YK, Yoo H, Jung DH, Moh I, Kim HJ, Jung SW, Na DK, Chang SC, Lee SM, Kim SJ, Oh J, Noh JW, Lee S

  • KMID: 1834867
  • Korean J Nephrol.
  • 2011 Mar;30(2):178-182.
Cyclosporine is an immunosuppressive agent that plays an important therapeutic role for organ transplantation. However, complications due to type 1 renal tubular acidosis, albeit rare, have been reported. We experienced...
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Renal Tubular Acidosis

Park HW

  • KMID: 2196733
  • J Korean Soc Pediatr Nephrol.
  • 2010 Oct;14(2):120-131.
Renal tubular acidosis (RTA) is a metabolic acidosis due to impaired excretion of hydrogen ion, or reabsorption of bicarbonate, or both by the kidney. These renal tubular abnormalities can occur...
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A Case of Distal Renal Tubular Acidosis and Sjogren's Syndrome in a Patient with Autoimmune Thyroiditis

An HR, Bae SC, Lee KB, Lee YK, Kim JK, Park HC, Ha SK, Lee JE

  • KMID: 2080056
  • Korean J Nephrol.
  • 2010 Jan;29(1):89-93.
A 52-year old woman, who had hypothyroidism associated with autoimmune thyroiditis for 5 years, was hospitalized for tingling sensation and muscle weakness of both lower extremities. Her initial laboratory findings...
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Electrolyte and Acid-Base Disturbances Associated with Non-Steroidal Anti-Inflammatory Drugs

Kim S, Joo KW

Inhibition of renal prostaglandin synthesis by non-steroidal anti-inflammatory drugs (NSAIDs) causes various electrolyte and acid-base disturbances including sodium retention (edema, hypertension), hyponatremia, hyperkalemia, and decreased renal function. Decreased sodium excretion...
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A Case of Mixed Type Renal Tubular Acidosis with Primary Sjogren`s Syndrome

Lee DH, Lee YK, Kim JK, Kim M, Sung CW, Jang JH, Noh JW

  • KMID: 2307220
  • Korean J Nephrol.
  • 2007 Sep;26(5):619-624.
56-year old woman was hospitalized for severe weakness and generalized bone pain, so she was immediately evaluated for the multiple bone lesions under the impression of malignancy with bone metastasis...
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A Case of Toluene-induced Renal Tubular Acidosis Presented with Hypokalemic Paralysis

Park JJ, Chang H, Jung JY, Jung SJ, Song KH, Suh WN, Chun SW, Lee HY, Yoo TH

  • KMID: 2331499
  • J Korean Soc Emerg Med.
  • 2006 Dec;17(6):656-658.
Toluene is known to cause a moderate degree of hypokalemia, myalgia, and even muscular weakness. We encountered the patient with acute hypokalemic paralysis in a chronic glue sniffer. A 32-year-old...
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A Case of Proximal Renal Tubular Acidosis Accompanied by Vitamin D Deficient Rickets

Kwon SY, Choi YJ, Kim KH

  • KMID: 1578220
  • J Korean Soc Pediatr Nephrol.
  • 2006 Apr;10(1):58-64.
In the clinical state of vitamin D deficiency, it is possible that associated phosphate depletion, parathyroid hormone excess, and hypocalcemia may all depress the proximal tubular reabsorption of bicarbonate, in...
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A Case of Distal Renal Tubular Acidosis by Damage of H+-ATPase Pump after Paraquat Intoxication

Gil HW, Song MS, Yang JO, Lee EY, Hong SY, Kim J

  • KMID: 2254328
  • Korean J Nephrol.
  • 2004 Jul;23(4):685-689.
Distal Renal tubular acidosis is characterized by tubular dysfunction with a decrease in net H+-secretion in the collecting tubules regardless of normal glomerular filtration rate. It classified into primary and...
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