J Korean Rheum Assoc.  2000 Jun;7(2):179-184.

A Case of Primary Sjorgen's Syndrome Presenting as Hypokalemic Periodic Paralysis

Affiliations
  • 1Department of Internal Medicine Pochon CHA University of Medicine, Kyongi-do Korea.

Abstract

We describe a 46-year-old woman with hypokalemic paralysis as the initial manifestation of Sjorgen's syndrome. Sjorgen's syndrome is an autoimmune exocrinopathy, characterized by keratoconjuntivitis sicca and xerostomia. Among the extraglandular manifestations of Sjorgen's syndrome, renal tubular involvement, especially renal tubular acidosis, is the most often latent or minimally symptomatic. Renal tubular acidosis is estimated to be present in 25~30 percent of the cases. Hypokalemic paralysis may serve as a clinical marker for more severe renal disease in patient who has primary Sjorgen's syndrome with renal tubular acidosis, even though it is a rare manifestation of Sjorgen's syndrome.

Keyword

Hypokalemic paralysis; Renal tubular acidosis; Sjorgen's syndrome

MeSH Terms

Acidosis, Renal Tubular
Biomarkers
Female
Humans
Hypokalemic Periodic Paralysis*
Middle Aged
Paralysis
Xerostomia
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