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J Korean Rheum Assoc.  2009 Mar;16(1):38-42. 10.4078/jkra.2009.16.1.38.

A Case of Henoch-Schonlein Purpura Associated with Idiopathic Thrombocytopenic Purpura

Affiliations
  • 1Department of Allergy and Rheumatology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea. chsuh@ajou.ac.kr

Abstract

Henoch-Schonlein purpura (HSP) is rarely associated with other autoimmune diseases. We experienced a case of HSP that was associated with idiopathic thrombocytopenic purpura (ITP). A 65-year old male patient complained of fever, purpura, generalized edema and arthralgia. He was diagnosed with HSP and his condition was improved with high-dose corticosteroid treatment. In 12 weeks, the symptoms of HSP were improving, however a thrombocytopenia developed. There was no reasonable cause for thrombocytopenia on the evaluation. He was diagnosed with ITP after bone marrow biopsy. Due to the refractory thrombocytopenia, which didn't respond to other medical treatments, we then performed splenectomy and the patient showed a good response. We report here on the first case of HSP and ITP, and we include a review of the related literature.

Keyword

Henoch-Schonlein purpura; Idiopathic thrombocytopenic purpura; Splenectomy

MeSH Terms

Arthralgia
Autoimmune Diseases
Biopsy
Bone Marrow
Edema
Fever
Humans
Male
Purpura
Purpura, Schoenlein-Henoch
Purpura, Thrombocytopenic, Idiopathic
Splenectomy
Thrombocytopenia
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