J Korean Soc Transplant.
2005 Dec;19(2):219-220.
Kidney Transplantation in a Patient with Idiopathic Thrombocytopenic Purpura
- Affiliations
-
- 1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. yukim@yumc.yonsei.ac.kr
- 2Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by the presence of IgG autoantibody against platelet, low platelet count, and bleeding disorders. Anecdotal experience of renal transplantation adopting the use of 2 weeks of steroids treatment, perioperative intravenous immunoglobulin, and simultaneous splenectomy in a patient with ITP was reported recently. However, advantage of these procedures is not yet confirmed. Recently, we performed a case of uneventful renal transplantation in a patient with ITP without immunoglobulin treatment and no splenectomy. Although platelet counts have been under normal limit after transplantation, the anti-platelet antibody converted to negative postoperatively and the graft function has been stable until now. Our case report raised the question about the use of perioperative immunoglobulin and splenectomy in these particular patient groups waiting for renal transplantation.
