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Cortisol Measurements in Cushing's Syndrome: Immunoassay or Mass Spectrometry?

Casals G, Hanzu FA

Determination of cortisol levels in the urine (24 hours urine free cortisol), saliva (late-night), or serum (total cortisol after dexamethasone suppression) is recommended to screen for Cushing's syndrome (CS). This...
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Current Diagnosis and Management of Hypersensitivity Pneumonitis

Leone PM, Richeldi L

Hypersensitivity Pneumonitis (HP) one of the most common interstitial lung diseases (ILDs) is characterized by exposure to an inhaled inciting antigen that leads to a host immunologic reaction determining interstitial...
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Acute Leukemia Relapse Presenting as Recurrent Involvement of the Optic Nerve

Lee SY, Yoon JH, Chung SA

PURPOSE: To report two cases with recurrent involvement of the optic nerve as the initial sign of acute leukemic relapse. CASE SUMMARY: An 8-year-old male with acute lymphoblastic leukemia on the...
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Clinical Characteristics and Treatment of Immune-Related Adverse Events of Immune Checkpoint Inhibitors

Choi J, Lee SY

Immune checkpoint inhibitors (ICIs) have been changing the paradigm of cancer treatment. However, immune-related adverse effects (irAEs) have also increased with the exponential increase in the use of ICIs. ICIs...
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A case of toxic epidermal necrolysis induced by cytomegalovirus infection followed by DRESS (drug reaction with eosinophilia and systemic symptoms)

Sim DW, Son S, Yu J, Koh YI

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. Although viral reactivation is associated with DRESS syndrome, its role in...
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Reversal of Olfactory Disturbance in Allergic Rhinitis Related to OMP Suppression by Intranasal Budesonide Treatment

Jung AY, Kim YH

PURPOSE: We evaluated the severity of olfactory disturbance (OD) in the murine model of allergic rhinitis (AR) and local allergic rhinitis (LAR) in mice. We also investigated the therapeutic effect...
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A Case of Immunoglobulin A Pemphigus: Intraepidermal Neutrophilic Dermatosis Type

Heo JH, Yoon HS, Lee SH, Yeom SD, Kim L, Kim SC, Byun JW, Shin J, Choi GS

  • KMID: 2465959
  • Korean J Dermatol.
  • 2019 Sep;57(8):492-495.
Immunoglobulin A (IgA) pemphigus is a rare variant of an autoimmune bullous disease with IgA antibodies. IgA pemphigus is divided into 2 major subtypes: the subcorneal pustular dermatosis (SPD) type...
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Radiation-induced Myositis after Proton Beam Therapy to Huge Hepatocellular Carcinoma

Kim J, Yoo GS, Sinn DH, Park HC, Koh KC

Proton beam therapy (PBT) is one of the advances in radiotherapy techniques, which enables dose escalation with lower probability of radiation-induced liver or gastrointestinal injuries. However, the chest wall proximal...
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Epidemiology of C5 Palsy after Cervical Spine Surgery: a 21-Center Study

Oh JK, Hong JT, Kang DH, Kim SW, Kim SW, Kim YJ, Chung CK, Shin JJ, Yi S, Lee JK, Lee JH, Lee CH, Lee HJ, Chun HJ, Cho DC, Cho YE, Jin YJ, Choi KC, Han IH, Hyun SJ, Hur JW, Kim KJ

OBJECTIVE: C5 palsy is a severe complication after cervical spine surgery, the pathophysiology of which remains unclear. This multicenter study investigated the incidence of C5 palsy following cervical spine surgery...
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Eosinophilic Enteritis Presenting as Massive Ascites after Influenza A Virus Infection in a Young Female

Kim MJ, Oh MJ

Eosinophilic gastrointestinal disorder (EGID) is an uncommon disease that is accompanied by intestinal eosinophil infiltration without a secondary cause of eosinophilia. Eosinophilic enteritis is a secondary portion of EGID that...
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Effects of dexamethasone and hydrocortisone on rocuronium-induced neuromuscular blockade and reversal by sugammadex in phrenic nerve-hemidiaphragm rat model

Choi H, Park SY, Kim YB, In J, Yang HS, Lee JS, Kim S, Park S

BACKGROUND: The facilitator effects of steroids on neuromuscular transmission may cause resistance to neuromuscular blocking agents. Additionally, steroids may hinder sugammadex reversal of neuromuscular blockade, but these findings remain controversial....
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Clinco-pathologic Features of Alopecia in a Patient of Cronkhite-Canada Syndrome

Seong GH, Shon U, Park MJ, Park M, Hong SP, Kim MH, Park BC

  • KMID: 2457691
  • Korean J Dermatol.
  • 2019 Aug;57(7):391-394.
Although hair loss in Cronkhite-Canada syndrome (CCS) developed frequently, its exact mechanism has not been elucidated. Thus, we attempted to investigate the histopathologic features of hair loss with scalp biopsy...
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Pustulotic Arthro-osteitis Improved with Anti TNF-α Inhibitor

Park HS, Kim JH, Kim HW, Kim SC

  • KMID: 2457688
  • Korean J Dermatol.
  • 2019 Aug;57(7):378-382.
Pustulotic arthro-osteitis (PAO) is a rare chronic inflammatory disorder characterized by inflammatory osteitis of the sternoclavicular joint and palmoplantar pustulosis. Here, we report a case of PAO that was successfully...
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A Case of Autoimmune Sensorineural Hearing Loss Responding to Cytotoxic Agent

Lee YW, Lee J, Kim MB, Chang SO

Autoimmune sensorineural hearing loss is a rare disease characterized by bilateral sensorineural hearing loss, some in a progressive pattern and others in idiopathic or fluctuating pattern, often accompanied by vestibular...
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The Korean Organ Transplant Registry (KOTRY): Second Official Adult Heart Transplant Report

Kim D, Choi JO, Oh J, Cho HJ, Jung SH, Lee HY, Kang SM, Kim JJ, Jeon ES

BACKGROUND AND OBJECTIVES: This second adult heart transplantation (HTx) report is based on Korean Organ Transplant Registry data submitted on 400 HTxs in recipients of all ages. METHODS: From March 2014...
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Two Case Reports of a Purtscher-like Retinopathy Occurring after Retrobulbar Anesthesia

Jeong IW, Choi CW, Ko SJ

PURPOSE: Although there are significant risks, retrobulbar anesthesia is commonly used for eye surgery. We report two cases of Purtscher-like retinopathy, a rare complication. CASE SUMMARY: (Case 1) A 76-year-old female...
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Association Between High Neutrophil to Lymphocyte Ratio and Delayed Recovery From Bell's Palsy

Kim HS, Jung J, Dong SH, Kim SH, Jung SY, Yeo SG

OBJECTIVES: Factors predictive of the severity of and recovery from Bell's palsy remain unclear. This study evaluated the association between neutrophil to lymphocyte ratio (NLR) and the severity of and...
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Synergistic Effect of H1-Antihistamines on Topical Corticosteroids for Pruritus in Atopic Dermatitis: A Systematic Review and Meta-Analysis

Hur MS, Choe YB, Ahn KJ, Lee YW

BACKGROUND: Although oral antihistamines (H1-histamine receptor antagonists) are the main treatment option for pruritus in general skin dermatosis, their effect in treating pruritus of atopic dermatitis (AD) has not yet...
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A survey of patients’ perspectives of steroid injection (ppyeojusa) in Korea

Shin BM, Hong SJ, Lim YH, Jeong JH, Moon HS, Choi HR, Park SK, Han RJ, Kim JH

BACKGROUND: Steroid injections are commonly used in pain clinics to relieve pain and treat inflammation. In Korea, these steroid injections are well known as ‘ppyeojusa’, which means to inject into...
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Systemic effects of fluoroscopically guided epidural steroid injection with dexamethasone

Kang WY, Lee JW, Lee E, Kang Y, Ahn JM, Kang HS

BACKGROUND: Epidural steroid injections (ESIs) have been widely used in managing spinal pain. Dexamethasone has recently emerged as a useful drug in this setting, relative to particulate steroids, although the...
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