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Cortisol Measurements in Cushing's Syndrome: Immunoassay or Mass Spectrometry?

Casals G, Hanzu FA

Determination of cortisol levels in the urine (24 hours urine free cortisol), saliva (late-night), or serum (total cortisol after dexamethasone suppression) is recommended to screen for Cushing's syndrome (CS). This...
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Current Diagnosis and Management of Hypersensitivity Pneumonitis

Leone PM, Richeldi L

Hypersensitivity Pneumonitis (HP) one of the most common interstitial lung diseases (ILDs) is characterized by exposure to an inhaled inciting antigen that leads to a host immunologic reaction determining interstitial...
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Acute Leukemia Relapse Presenting as Recurrent Involvement of the Optic Nerve

Lee SY, Yoon JH, Chung SA

PURPOSE: To report two cases with recurrent involvement of the optic nerve as the initial sign of acute leukemic relapse. CASE SUMMARY: An 8-year-old male with acute lymphoblastic leukemia on the...
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Clinical Characteristics and Treatment of Immune-Related Adverse Events of Immune Checkpoint Inhibitors

Choi J, Lee SY

Immune checkpoint inhibitors (ICIs) have been changing the paradigm of cancer treatment. However, immune-related adverse effects (irAEs) have also increased with the exponential increase in the use of ICIs. ICIs...
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A case of toxic epidermal necrolysis induced by cytomegalovirus infection followed by DRESS (drug reaction with eosinophilia and systemic symptoms)

Sim DW, Son S, Yu J, Koh YI

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. Although viral reactivation is associated with DRESS syndrome, its role in...
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Reversal of Olfactory Disturbance in Allergic Rhinitis Related to OMP Suppression by Intranasal Budesonide Treatment

Jung AY, Kim YH

PURPOSE: We evaluated the severity of olfactory disturbance (OD) in the murine model of allergic rhinitis (AR) and local allergic rhinitis (LAR) in mice. We also investigated the therapeutic effect...
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Comparison of Treatment Outcomes between Intratympanic Steroid Injection and Oral Diuretics in Patients with Acute Low Frequency Sensorineural Hearing Loss with Vertigo

An YH, Shim HJ

OBJECTIVES: Sudden sensorineural hearing loss and Meniere disease can be managed with intratympanic steroid injection (ITSI) as a primary treatment. The aim of this study was to compare the effectiveness...
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The Effect of Steroid Therapy for Idiopathic Unilateral Vocal Cord Palsy

Bae JW, Lee G

BACKGROUND AND OBJECTIVES: Idiopathic unilateral vocal fold paralysis (IVFP) is believed to be due to inflammation and edema of the recurrent laryngeal nerve caused by viral diseases such as upper...
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The problem of medicating women like the men: conceptual discussion of menstrual cycle-dependent psychopharmacology

Yum SK, Yum SY, Kim T

While hormonal changes during the ovulatory cycles affect multiple body systems, medical management, including medication dosing remains largely uniform between the sexes. Little is known about sex-specific pharmacology in women....
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Sepsis

Lee Y, Cho YJ

Diagnosis and treatment criteria were recently updated based on the Sepsis-3 guidelines, which recommend the sequential organ failure assessment for accurate characterization of organ dysfunction. Large randomized controlled trials have...
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Nonarteritic Anterior Ischemic Optic Neuropathy with an Atypical Visual Field Defect

Song DH, Lee JE

PURPOSE: To report a case of nonarteritic anterior ischemic optic neuropathy (NA-AION) with an atypical visual field defect after intraocular surgery. CASE SUMMARY: A 61-year-old male presented with a visual field...
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Long-term Follow-up Results of Patients with Welding-arc Maculopathy Assessed Using Spectral Domain Optical Coherence Tomography

Kim JH, Kim BJ, Kang TS, Cho HK, Nam KY, Yoo JM, Han YS

PURPOSE: We present four cases of welding arc maculopathy as observed using spectral-domain optical coherence tomography (SD-OCT). CASE SUMMARY: Four patients, who performed welding without wearing protective eye gear, presented to...
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Metastatic Small Cell Neuroendocrine Carcinoma to the Orbit Manifesting as Total Ophthalmoplegia

Lee JH, Lee EC, Lee HW, Oh SY

PURPOSE: To report a case of primary ureteral small cell neuroendocrine carcinoma metastasis in the left orbital wall, with a review of the literature. CASE SUMMARY: A 79-year-old male visited our...
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The Effect of Topical 10% N-acetylcysteine on Refractory Filamentary Keratitis

Lim HR, Koh JW

PURPOSE: To analyze the effects of topical 10% N-acetylcysteine on patients with refractory filamentary keratitis. METHODS: The present study included 29 eyes from 20 patients diagnosed with filamentary keratitis. We analyzed...
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Perinatal Risk Factors for Postnatal Weight Loss in Late Preterm Infants

Bae SP, Song JH, Hahn WH, Koh JW, Kim H

PURPOSE: Many studies have reported associations of early postnatal growth failure in preterm infants with several morbidities. However, the risk factors for postnatal weight loss (PWL) in late preterm infants...
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Inhaled Corticosteroids and Placebo Treatment Effects in Adult Patients With Cough: A Systematic Review and Meta-analysis

Lee SE, Lee JH, Kim HJ, Lee BJ, Cho SH, Price D, Morice AH, Song WJ

PURPOSE: Inhaled corticosteroids (ICSs) are often considered an empirical therapy in the management of patients with cough. However, ICS responsiveness is difficult to interpret in daily clinical practice, as the...
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Inhaled Corticosteroids in Asthma and the Risk of Pneumonia

Kim MH, Rhee CK, Shim JS, Park SY, Yoo KH, Kim BY, Bae HW, Sim YS, Chang JH, Cho YJ, Lee JH

PURPOSE: Asthma is a common disease that is expensive and burdensome for patients. Inhaled corticosteroids (ICS) are the most important drugs for asthma treatment and are often prescribed long-term. However,...
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Successful Treatment of Glycine-Receptor-Antibody-Mediated Progressive Encephalomyelitis with Rigidity and Myoclonus by Combining Steroids and Azathioprine

Lee EJ, Kim K, Choi JY, Park KS

No abstract available.
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A Boy with Chronic Active EBV Infection Presented as Mosquito Bite Hypersensitivity Progressed to Fatal Hemophagocytic Lymphohistiocytosis due to NK Cell Neoplasm

Lee JA, Han SB, Chung NG, Kang JH, Kim M, Jeong DC

Chronic active Epstein-Barr virus (CAEBV) infection is characterized by recurrent infectious mononucleosis (IM)-like symptoms and an unusual pattern of anti-EBV antibodies. We report a boy with CAEBV who progressed to...
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Are steroids required in the treatment of ganglion impar blockade in chronic coccydynia? a prospective double-blinded clinical trial

Sencan S, Edipoglu I, Demir FG, Yolcu G, Gunduz OH

BACKGROUND: Ganglion impar blockade is a reliable and effective treatment option used in patients with coccydynia. Our primary objective was to specify the role of corticosteroids in impar blockade. We...
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