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Clinical Features and Treatment Outcomes of Immune Thrombocytopenic Purpura in Infants: A Single Center Retrospective Study

Sohn SJ, Park KM, Yang EJ, Lim YT

BACKGROUND: Immune thrombocytopenic purpura (ITP) in children less than one year of age is less well characterized compared to ITP in toddlers and school-age children. Since children of different ages...
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A case of immune thrombocytopenia associated with invasive thymoma successfully treated with eltrombopag

Yoon JK, Jang HR, Park JH, Kim KH, Roh EY, Byun JM

No abstract available.
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Methylprednisolone versus intravenous immune globulin as an initial therapy in adult primary immune thrombocytopenia

Kim CH, Choi YS, Moon JY, Kim DY, Lee SY, Lee HJ, Yun HJ, Kim S, Jo DY, Song IC

BACKGROUND/AIMS: Few studies have addressed whether there are differences in clinical efficacy between intravenous methylprednisolone (methyl-Pd) and intravenous immunoglobulin (IVIg) use. METHODS: We retrospectively compared platelet responses and toxicities associated with...
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The Efficacy of High Dose Dexamethasone Therapy in Children with Immune Thrombocytopenic Purpura

Lee HO, Chang SH, Baek HJ, Kim HS, Park SM, Shin MG, Kook H

BACKGROUND: Few studies of high dose dexamethasone (HD-DXM) therapy in children with immune thrombocytopenic purpura (ITP) have been reported. The purpose of this study is to investigate efficacy and safety...
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Clinical Courses and Outcome of Newly Diagnosed Immune Thrombocytopenia in Infants

Hwang NR, Park KD

BACKGROUND: Infants with immune thrombocytopenia (ITP) are at increased risk of high risk bleeding and vaccination-associated ITP. Infants with ITP respond favorably to treatment and are less likely to develop...
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Efficacy and Safety of a New 10% Intravenous Immunoglobulin Product in Patients with Primary Immune Thrombocytopenia (ITP)

Hong J, Bang SM, Mun YC, Yhim HY, Lee J, Lim HS, Oh D, on behalf of the Korean GC IVIg Investigators

BACKGROUND: In the current study, we aimed to investigate the efficacy and safety of intravenous immunoglobulin (IVIg)-SN 10%, a new 10% IVIg formulation, in adult patients with severe primary immune...
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Diagnostic Approach of Childhood Immune Thrombocytopenia

Kim JY

Immune thrombocytopenia (ITP) is the most common cause of thrombocytopenia in children and can be defined as an autoimmune disorder of isolated thrombocytopenia without other causes of thrombocytopenia. This review...
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New synergistic efficacy of combination of romiplostim and steroid in refractory immune thrombocytopenia patients

Yoon JS, Lee YJ, Baek DW, Park HY, Park BE, Moon JH, Sohn SK

No abstract available.
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Life-threating outcomes after dental implantation in patient with idiopathic thrombocytopenic purpura: a case report and review of literature

Lee ST, Kim JW, Kwon TG

BACKGROUND: Patients with chronic ITP (idiopathic thrombocytopenia) frequently do not require comprehensive medication for daily life. Usually, it had been regarded that postoperative bleeding after a simple or surgical extraction...
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Interleukin-1B (IL-1B-31 and IL-1B-511) and interleukin-1 receptor antagonist (IL-1Ra) gene polymorphisms in primary immune thrombocytopenia

Yadav DK, Tripathi A, Gupta D, Shukla S, Singh AK, Kumar A, Agarwal J, Prasad KN

BACKGROUND: Immune thrombocytopenia (ITP) is an immune-mediated disease caused by autoantibodies against platelets membrane glycoproteins GPIIb/IIIa and GPIb/IX. The etiology of ITP remains unclear. This study evaluated the association of...
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Management of immune thrombocytopenia: Korean experts recommendation in 2017

Jang JH, Kim JY, Mun YC, Bang SM, Lim YJ, Shin DY, Choi YB, Yhim HY, Lee JW, Kook H, on the behalf of Korean Aplastic Anemia Working Party

Management options for patients with immune thrombocytopenia (ITP) have evolved substantially over the past decades. The American Society of Hematology published a treatment guideline for clinicians referring to the management...
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Clinical Course of Childhood Immune Thrombocytopenic Purpura and Analysis Predicting Factor of Prognosis

Lee T, Choi J, Lim YJ

BACKGROUND: Immune thrombocytopenic purpura (ITP) is an acquired bleeding disorder in which the immune system destroys platelets. There were many studies which predicted the factors associated with the prognosis of...
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Dapsone therapy for refractory immune thrombocytopenia patients: a case series

Lee JY, Lee JO, Jung JY, Bang SM

BACKGROUND: Dapsone has been recommended as a second-line immunosuppressive agent for patients with immune thrombocytopenia (ITP). METHODS: We retrospectively analyzed the efficacy and safety of dapsone therapy in patients with ITP. RESULTS:...
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Dapsone therapy for immune thrombocytopenic purpura: old but still unfamiliar

Song J

No abstract available.
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Aseptic Meningitis and Acute Kidney Injury after Immunoglobulin Infusion in a Patient with Systemic Lupus Erythematosus and Immune Thrombocytopenic Purpura

Jo S, Oh EH, Lee JY, Cho YK, Kwon OC, Ghang B, Kim YG

A 36-yr-old woman with systemic lupus erythematosus was admitted in our center because of thrombocytopenia that was being treated with corticosteroids. She was prescribed a four-day course of intravenous immunoglobulin...
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Successful treatment of steroid-refractory immune thrombocytopenia with alemtuzumab

Jung CW, Cho SH, Park S, Jang JH, Ji JH

No abstract available.
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Effect of short-term, high-dose methylprednisolone on oxidative stress in children with acute immune thrombocytopenia

Cura M, Koç A, Aksoy N, Özdemir Z

BACKGROUND: Immune thrombocytopenia (ITP) is the most common cause of acquired childhood thrombocytopenia and is characterized by increased immune-mediated destruction of circulating thrombocytes. Oxidative damage may be involved in ITP...
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Neutrophil to Lymphocyte Ratio (NLR) as a Predictive Marker for Prognosis in the Patients with Immune Thrombocytopenic Purpura (ITP)

Yang GE, Lee MJ, Yoo JH, Chueh HW

BACKGROUND: Immune thrombocytopenic purpura (ITP) is an autoimmune disorder presenting low platelet count in peripheral blood without any other abnormalities in other blood cell lineage. There were many studies that...
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Clinical course and prognostic factors of childhood immune thrombocytopenia: single center experience of 10 years

Jung JY, O AR, Kim JK, Park M

PURPOSE: This study aimed to evaluate the clinical course of childhood immune thrombocytopenia (ITP) and to assess the risk factors for developing chronic ITP. METHODS: The records of 64 children diagnosed...
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Platelet count recovery after intravenous immunoglobulin predicts a favorable outcome in children with immune thrombocytopenia

Choi HS, Ji MH, Kim SJ, Ahn HS

BACKGROUND: Childhood immune thrombocytopenic purpura (ITP) is a common acquired bleeding disorder. Even though most children recover, either spontaneously or with therapy, 10-20% of newly diagnosed ITP cases have a...
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