J Korean Assoc Oral Maxillofac Surg.  2004 Apr;30(2):165-169.

Necrosis of a parotid gland pleomorphic adenoma: A case report

Affiliations
  • 1Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Dental Science Research Institute, Chonnam National University. ryu-suny@hanmail.net
  • 2Department of Oral Pathology, College of Dentistry, Dental Science Research Institute, Chonnam National University.

Abstract

Pleomorphic adenoma is the most common neoplasm of the parotid gland, generally presenting as a slowly growing, firm, well-circumscribed, painless nodule. It is often difficult to separate into benign and malignant categories because its bland histomorphologic and cytologic features. This tumor can be rarely associated with cystic change, hemorrhagic necrosis, or spontaneous infarction. Necrosis of lesional tissue may be associated with malignant transformation, particularly in a pleomorphic adenoma. We report a case of 50-year-old woman presented with a enlarging right parotid mass. Computed tomographic scan demonstrated a right superficial lobe mass with ill-defined border. The preoperative fine needle aspiration yielded necrotic debris and atypical squamous elements that were thought to be compatible with high degree of mucoepidermoid carcinoma. A total parotidectomy with intraoperative frozen section revealed extensive necrosis and diagnosed as malignant tumor. This tumor was finally diagnosed as a pleomorphic adenoma with necrosis on permanent sections. Caution should be exercised in evaluation of the parotid neoplasms with central necrosis to avoid misdiagnosis of such lesions as malignancy.

Keyword

Parotid gland; Pleomorphic adenoma; Necrosis; Malignancy

MeSH Terms

Adenoma, Pleomorphic*
Biopsy, Fine-Needle
Carcinoma, Mucoepidermoid
Diagnostic Errors
Female
Frozen Sections
Humans
Infarction
Middle Aged
Necrosis*
Parotid Gland*
Parotid Neoplasms
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