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Noninvasive follicular thyroid neoplasm with papillary-like nuclear features: its updated diagnostic criteria, preoperative cytologic diagnoses and impact on the risk of malignancy

Na HY, Park SY

Due to the extremely indolent behavior, a subset of noninvasive encapsulated follicular variant papillary thyroid carcinomas has been classified as “noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)” since...
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Evaluation of In-Hospital Cluster of COVID-19 Associated With a Patient With Prolonged Viral Shedding Using Whole-Genome Sequencing

Jung J, Lee J, Kim SK, Park S, Lim YJ, Kim EO, Park H, Park MS, Kim SH

Background: Patients with hematologic malignancies may produce replication-competent virus beyond 20 days of SARS-CoV-2 infection. However, data regarding the transmission of SARS-CoV-2 from patients with prolonged viral shedding is limited. Methods:...
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Malignancy risk of thyroid nodules with minimal cystic changes: a multicenter retrospective study

Lee YJ, Kim JY, Na DG, Kim Jh, Oh M, Kim DB, Yoon RG, Kim SK, Bak S

Purpose: The aim of this multicenter study was to investigate the malignancy risk of minimally cystic thyroid nodules (MCTNs) using cyto-histopathologic diagnoses as the reference standard. Methods: From June 2015 to...
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Pediatric living donor liver transplantation for biliary embryonal rhabdomyosarcoma: a case report of a case showing disease-free survival over 2 years

Namgoong JM, Hwang S, Park GC, Kwon H, Ha S, Oh SH, Kim KM

Biliary rhabdomyosarcoma is a rare tumor, but it is still the most common tumor of the biliary tract in children. We report a case of a 6-year-old boy with biliary...
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Development and Validation of 18F-FDG PET/CT-Based Multivariable Clinical Prediction Models for the Identification of Malignancy-Associated Hemophagocytic Lymphohistiocytosis

Yang X, Lu X, Liu J, Kan Y, Wang W, Zhang S, Liu L, Li J, Yang J

Objective: 18F-fluorodeoxyglucose (FDG) PET/CT is often used for detecting malignancy in patients with newly diagnosed hemophagocytic lymphohistiocytosis (HLH), with acceptable sensitivity but relatively low specificity. The aim of this study...
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Clinical Efficacy and Safety of Arbekacin against Pneumonia in Febrile Neutropenia: A Retrospective Study in Patients with Hematologic Malignancies

Ohashi T, Fujita Y, Irisawa H, Nakaminami H, Arai T, Takahashi M, Momiyama E, Murata N, Murayama K, Saito T

Background: Arbekacin (ABK) is an aminoglycoside that exhibits anti-methicillin-resistant Staphylococcus aureus (MRSA) and anti-Pseudomonas aeruginosa activities. Therefore, for patients with febrile neutropenia (FN) and concurrent pneumonia suspected to be caused...
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An Adenocarcinoma Associated with Bilateral, Diffuse, Uveal Melanocytic Proliferation

Chung W, Kim SH, Choi Y, Choi SK, Lee JJ, Park SW, Byon IS

Purpose: We report bilateral, diffuse, uveal melanocytic proliferation caused by a stomach adenocarcinoma. Case summary: A 78-year-old male complained of visual impairment 3 months in duration. He had diabetes and had...
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Investigation of serum survivin in dogs suffering from cancer: a multicenter study

Estaller A, Kessler M, Wehrend A, Gessler F, Hirschberger J, Neumann S

Background: In contrast to human medicine, only a small number of serum tumor markers are established in veterinary medicine even though they are a non-invasive diagnostic tool. Objectives: This study examined...
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RUNX1 Germline Mutation in a Patient with Chronic Thrombocytopenia

Nam Y, Yeon GM, Kong SG

One of the pathophysiologic mechanism of inherited thrombocytopenia is a defect in transcription factors that regulate the expression of multiple genes required for megakaryopoiesis. Runt-related transcription factor 1 (RUNX1) binds...
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Haploidentical Family Donor Transplantation for Pediatric Hematologic Malignancies

Lee JW

Haploidentical family donor hematopoietic stem cell transplantation (Haplo-HSCT) has been increasingly used for patients who require transplant for optimum therapy, but lack a human leukocyte antigen (HLA)-matched donor. Important variables...
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Clinical Outcomes of Orbital Exenteration in Korean Patients with Orbital Malignancies

Son WY, Park NR, Kim SE, Yang SW

Purpose: We report the clinical outcomes of Korean patients who were diagnosed with orbital malignancies and underwent orbital exenteration. Methods: We retrospectively reviewed the tumor origins, histopathological diagnoses, local/regional recurrences, distant...
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Effectiveness and Safety of Clofarabine Monotherapy or Combination Treatment in Relapsed/Refractory Childhood Acute Lymphoblastic Leukemia: A Pragmatic, Non-interventional Study in Korea

Choi JY, Hong CR, Hong KT, Kang HJ, Kim S, Lee JW, Jang PS, Chung NG, Cho B, Kim H, Koh KN, Im HJ, Seo JJ, Hahn SM, Han JW, Lyu CJ, Yang EJ, Lim YT, Yoo KH, Koo HH, Kook H, Jeon IS, Cho H, Shin HY

Purpose Effectiveness and safety of clofarabine (one of the treatment mainstays in pediatric patients with relapsed/refractory acute lymphoblastic leukemia [ALL]) was assessed in Korean pediatric patients with ALL to facilitate...
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Sarcoid-Like Reaction after Complete Remission of Malignancy: CT and 18F-FDG PET/CT Features for the Differential Diagnosis from Lymph Node Metastasis

Kang HJ, Kim Y, Bae JY, Chang JH, Lee SH

Purpose To identify the imaging features indicative of sarcoid-like reactions in patients with intrathoracic lymphadenopathy after complete remission of malignancies. Materials and Methods This study enrolled five patients with histopathologically confirmed...
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Nosocomial Outbreak of COVID-19 in a Hematologic Ward

Jung J, Lee J, Jo S, Bae S, Kim JY, Cha HH, Lim YJ, Kwak SH, Hong MJ, Kim EO, Bae JY, Kang C, Sung M, Park MS, Kim SH

Background: Coronavirus disease 2019 (COVID-19) outbreaks occur in hospitals in many parts of the world. In hospital settings, the possibility of airborne transmission needs to be investigated thoroughly. Materials and Methods:...
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Management Strategy and Surveillance of Intraductal Papillary Mucinous Neoplasm–Gastroenterologist’s Viewpoint

Kim TH, Chon HK

The length, the frequency, and the methods of surveillance for intraductal papillary mucinous neoplasm (IPMN) of the pancreas are still debating. According to the recent guidelines, IPMN is stratified into...
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Clinicopathological Features of Patients Diagnosed with Both Primary Thyroid Cancer and Primary Renal Cell Cancer and Its Comparison with Patients with Thyroid Cancer or Renal Cell Cancer Alone

Park J, Kim YN, Ryoo H, Park H, Park SY, Kim TH, Chung JH, Seo SI, Kim SW

Background and Objectives: Thyroid cancer (TC) and renal cell carcinoma (RCC) display more frequent co-occurrence than would be expected by chance. We investigated clinicopathological features of patients with both primary...
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2020 Imaging Guidelines for Thyroid Nodules and Differentiated Thyroid Cancer: Korean Society of Thyroid Radiology

Lee JY, Baek JH, Ha EJ, Sung JY, Shin JH, Kim Jh, Lee MK, Jung SL, Lee YH, Ahn HS, Yoon JH, Choi YJ, Park JS, Lee YJ, Choi M, Na DG, Korean Society of Thyroid Radiology (KSThR) and Korean Society of Radiology

Imaging plays a key role in the diagnosis and characterization of thyroid diseases, and the information provided by imaging studies is essential for management planning. A referral guideline for imaging...
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Cyst Fluid Carcinoembryonic Antigen Level Difference between Mucinous Cystic Neoplasms and Intraductal Papillary Mucinous Neoplasms

Köker IH, Ünver N, Malya F, Uysal , Keskin EB, Şentürk H

Background/Aims: The role of cyst fluid carcinoembryonic antigen (CEA) level in differentiating mucinous pancreatic cystic lesions (PCLs) is controversial. We investigated the role of cyst fluid CEA in differentiating low-risk...
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Pancreatic metastasis from malignant phyllodes tumor of the breast

Lee SE, Bae YK, Choi JH

Pancreatic metastasis from malignant phyllodes tumor (PT) of the breast is rare, and only a few cases have been reported in the literature. Here, we report a case of pancreatic...
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Cancer incidence in the Tobruk area, eastern Libya: first results from Tobruk Medical Centre

Ismail F, Elsayed AG, El-Garawani I, Abdelsameea E

OBJECTIVES: Cancer is a major cause of morbidity and mortality worldwide, and it is an increasing problem in developing countries. Estimation of the incidence of cancer is important, especially in...
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