Blood Res.  2014 Sep;49(3):200-203. 10.5045/br.2014.49.3.200.

Bone marrow hypoplasia, isochromosome 8q and deletion of chromosome 6q preceding B-cell lymphoma

Affiliations
  • 1Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea. KAL119@yuhs.ac
  • 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 4Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Bone Marrow*
Isochromosomes*
Lymphoma, B-Cell*

Figure

  • Fig. 1 Initial bone marrow biopsy showed (A) aplastic marrow (hematoxylin and eosin stain, ×100). In August 2010, repeat biopsy showed (B) increased cellularity with abnormal lymphoid infiltration that was (C) positive for CD20 on immunohistochemical stain (×100).

  • Fig. 2 Giemsa-banded karyotype showing 46,XY,del(6)(q16),i(8)(q10) 9 months before evidence of B-cell lymphoma in the bone marrow. The abnormal chromosomes are marked by arrows.


Reference

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