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Treatment Patterns of Type 2 Diabetes Assessed Using a Common Data Model Based on Electronic Health Records of 2000–2019

Lee KA, Jin HY, Kim YJ, Im YJ, Kim EY, Park TS

Background: Real-world data analysis is useful for identifying treatment patterns. Understanding drug prescription patterns of type 2 diabetes mellitus may facilitate diabetes management. We aimed to analyze treatment patterns of type...
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Diagnosis for Pheochromocytoma and Paraganglioma: A Joint Position Statement of the Korean Pheochromocytoma and Paraganglioma Task Force

Ku EJ, Kim KJ, Kim JH, Kim MK, Ahn CH, Lee KA, Lee SH, Lee YB, Park KH, Choi YM, Hong N, Hong AR, Kang SW, Park BK, Seong MW, Kim M, Jung KC, Jung CK, Cho YS, Paeng JC, Kim JH, Ryu OH, Rhee Y, Kim CH, Lee EJ

Pheochromocytoma and paraganglioma (PPGLs) are rare catecholamine-secreting neuroendocrine tumors but can be life-threatening. Although most PPGLs are benign, approximately 10% have metastatic potential. Approximately 40% cases are reported as harboring...
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Trisomy 8 Associated Behçet’s Like Disease

Lee S, Choi WH, Kim JS, Lee KA, Jeon SR, Kim HS

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Primary hyperaldosteronism: a rare cause of acute aortic dissection

Jin HY, Lee KA

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Bicipitoradial Bursitis in a Patient With Behçet’s Disease

Choi WH, Kim JS, Lee KA, Kim HS

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Total ankylosis of the bilateral hand and wrist joints in a patient with ankylosing spondylitis

Kim SG, Lee KA

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Medication Utilization Analysis of Basiliximab as a Maintenance Immunosuppressant in Renal Failure Patients Undergoing Lung Transplantation

Seo Y, Geum MJ, Lee KA, Kim JS, Son ES, Yu YM

Background: Basiliximab is used as an alternative to tacrolimus in patients with decreased renal function. However, studies on basiliximab as a maintenance immunosuppressant, particularly in patients with lung transplantation, are...
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miR-4463 regulates aromatase expression and activity for 17β-estradiol synthesis in response to follicle-stimulating hormone

Lee SY, Kang YJ, Kwon J, Nishi Y, Yanase T, Lee KA, Koong MK

Objective The aim of this study was to investigate microRNAs (miRNAs) related to follicle-stimulating hormone (FSH) responsiveness using miRNA microarrays and to identify their target genes to determine the molecular...
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Diagnosis and Treatment of Growth Hormone Deficiency: A Position Statement from Korean Endocrine Society and Korean Society of Pediatric Endocrinology

Kim JH, Chae HW, Chin SO, Ku CR, Park KH, Lim DJ, Kim KJ, Lim JS, Kim G, Choi YM, Ahn SH, Jeon MJ, Hwangbo Y, Lee JH, Kim BK, Choi YJ, Lee KA, Moon SS, Ahn HY, Choi HS, Hong SM, Shin DY, Seo JA, Kim SH, Oh S, Yu SH, Kim BJ, Shin CH, Kim SW, Kim CH, Lee EJ

Growth hormone (GH) deficiency is caused by congenital or acquired causes and occurs in childhood or adulthood. GH replacement therapy brings benefits to body composition, exercise capacity, skeletal health, cardiovascular...
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Endometrial profilin 1: a key player in embryo-endometrial crosstalk

Lee CJ, Hong SH, Yoon MJ, Lee KA, Ko JJ, Koo HS, Kim JH, Choi DH, Kwon H, Kang YJ

Objective: Despite extensive research on implantation failure, little is known about the molecular mechanisms underlying the crosstalk between the embryo and the maternal endometrium, which is critical for successful pregnancy....
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Eupatilin treatment inhibits transforming growth factor beta-induced endometrial fibrosis in vitro

Lee CJ, Hong SH, Yoon MJ, Lee KA, Choi DH, Kwon H, Ko JJ, Koo HS, Kang YJ

Objective: Endometrial fibrosis, the primary pathological feature of intrauterine adhesion, may lead to disruption of endometrial tissue structure, menstrual abnormalities, infertility, and recurrent pregnancy loss. At present, no ideal therapeutic...
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Genetic Spectrum of UGT1A1 in Korean Patients with Unconjugated Hyperbilirubinemia

Kim JJ, Oh J, Kim Y, Lee KA

No abstract available.
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An optimized BRCA1/2 next-generationsequencing for different clinical sample types

Kim Y, Cho CH, Ha JS, Kim DH, Kwon SY, Oh SC, Lee KA

Objective: A simultaneous detection of germline and somatic mutations in ovarian cancer (OC) using tumor materials is considered to be cost-effective for BRCA1/2 testing. However, there are limited studies of...
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Nutrient intakes and medication use in elderly individuals with and without dry mouths

Lee KA, Park JC, Park YK

BACKGROUND/OBJECTIVES: The nutrition of the elderly depends on various factors. Oral health, especially oral dryness, can be an important risk factor. In this study, we attempted to determine whether dry...
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Management of Type 2 Diabetes Mellitus in Adolescents and Young Adults

Lee KA

Although type 1 diabetes remains more common among children and adolescents, the prevalence of obesity and type 2 diabetes among children, adolescents, and young adults is dramatically increasing. Young-onset type...
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Reconstruction of periorbital defects using a modified Tenzel flap

Cha JA, Lee KA

Background: Extensive eyelid defects are extremely challenging to reconstruct. Although numerous procedures for reconstructing periorbital defects have been proposed, no method is universally used. However, the Tenzel flap is the...
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Establishment of Reference Intervals for Serum Insulin-Like Growth Factor I in Korean Adult Population

Kim B, Cho Y, Ku CR, Lee SG, Lee KA, Kim JH

Appropriate reference intervals of serum insulin-like growth factor I (IGF-I) is important for diagnosing and monitoring patients with growth hormone-related diseases. To establish reference intervals, adult individuals (n=1,334, 680 men...
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Detection of Anti-Extractable Nuclear Antigens in Patients with Systemic Rheumatic Disease via Fluorescence Enzyme Immunoassay and Its Clinical Utility

Oh J, Park Y, Lee KA, Kim HS

PURPOSE: Testing for autoantibodies to extractable nuclear antigens (ENAs) plays an important role in the diagnosis and management of systemic rheumatic disease. Currently, no gold standard tests are available for...
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Intravenous Immunoglobulin Controls Th17 Cell-Mediated Osteoclastogenesis

Kim KW, Kim HR, Kim BM, Won JY, Lee KA, Lee SH

The purpose of this study was to determine the regulatory role of intravenous Ig (IVIg) in Th17 cytokine–induced RANK ligand (RANKL) expression and osteoclast (OC) differentiation from OC precursors (pre-OC)....
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Validation of Voriconazole Therapeutic Drug Monitoring in Lung Transplant Recipients Receiving Voriconazole alone for Treatment of Invasive Aspergillosis

Son YJ, Lee KA, Jo JH, Kim JS, Son ES, Park MS

BACKGROUND: Invasive aspergillosis (IA) is associated with high morbidity and mortality, particularly among immunocompromised patients, such as lung transplant recipients. Voriconazole, the first-line therapy for IA, shows a non-linear pharmacokinetic...
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