J Korean Med Sci.  2006 Feb;21(1):15-19. 10.3346/jkms.2006.21.1.15.

Risk Factor Analysis for Development of Asymptomatic Carotid Stenosis in Koreans

• Lim YJ
• Kim YW
• Choe YH
• Ki CS
• Park SK

• KMID: 2157775
• DOI: http://doi.org/10.3346/jkms.2006.21.1.15

Abstract

Many risk factors for atherosclerosis have been proposed to identify high risk individuals. We conducted a retrospective study to determine the risk factors for development of carotid stenosis (CS) in Koreans. Database of 2,805 subjects who underwent a check up of carotid artery for health examination were analyzed. Stenosis (%) of common carotid artery or proximal internal carotid artery was examined with ultrasonography. Subjects were divided into 2 groups (Group I; CS <10%, Group II; CS > or =30%). We compared demographic, laboratory and clinical data between 2 groups to determine the risk factors of CS. One hundred ninety seven subjects (7.0%) were categorized as Group II. At age- and sex-adjusted multivariate analysis, diabetes mellitus, hypertension, cerebrovascular disease, ischemic heart disease, hyperlipidemia, aspirin medication, current smoking, fasting glucose, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and leukocyte count were significant risk factors of CS. At stepwise logistic regression analysis, age, hypertension, hyperlipidemia, LDL-C and leukocyte count were independent risk factors. At subgroup analysis by smoking, age and leukocyte count were independent risk factors in smoker and age and hypertension in nonsmoker.

Keyword

Carotid Stenosis; Atherosclerosis; Risk Factors

MeSH Terms

Adult
Age Factors
Aged
Carotid Stenosis/blood/*epidemiology/etiology
Cholesterol/blood
Comparative Study
Female
Humans
Korea/epidemiology
Lipoproteins, LDL Cholesterol/blood
Logistic Models
Male
Middle Aged
Multivariate Analysis
Prevalence
Retrospective Studies
Risk Factors
Smoking/adverse effects

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