- Expanding the therapeutic landscape: ezetimibe as non-statin therapy for dyslipidemia
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Lee J, Lee SH
- KMID: 2547638
- Korean J Intern Med.
- 2023 Nov;38(6):797-809.
- doi: 10.3904/kjim.2023.243
Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, it can be challenging... -
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- Endovascular Treatment of Symptomatic Basilar Artery Stenosis
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Kim JH, Cho KC, Kim T, Ha SW, Suh SH
- KMID: 2547278
- Neurointervention.
- 2023 Nov;18(3):166-171.
- doi: 10.5469/neuroint.2023.00437
Purpose: While symptomatic basilar artery (BA) stenosis is associated with a higher risk of recurrent stroke or death, there is no consensus on the management of these patients who are... -
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- Coronary Artery Calcium Score as a Sensitive Indicator of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus: A Long-Term Cohort Study
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Koo DJ, Lee MY, Moon SJ, Kwon H, Lee SM, Park SE, Park CY, Lee WY, Oh KW, Cho SR, Jeong YH, Rhee EJ
- KMID: 2546987
- Endocrinol Metab.
- 2023 Oct;38(5):568-577.
- doi: 10.3803/EnM.2023.1770
Background: Coronary artery calcium score (CACS) has become an important tool for evaluating cardiovascular disease (CVD). This study evaluated the significance of CACS for future CVD through more than 10... -
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- Mechanisms of the Wnt Pathways as a Potential Target Pathway in Atherosclerosis
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Poznyak AV, Sukhorukov VN, Popov MA, Chegodaev YS, Postnov AY, Orekhov AN
- KMID: 2546556
- J Lipid Atheroscler.
- 2023 Sep;12(3):223-236.
- doi: 10.12997/jla.2023.12.3.223
The proteins of the Wnt family are involved in a variety of physiological processes by means of several canonical and noncanonical signaling pathways. Wnt signaling has been recently identified as... -
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- Metformin Reduces the Progression of Atherogenesis by Regulating the Sestrin2-mTOR Pathway in Obese and Diabetic Rats
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Sundararajan S, Jayachandran I, Pandey GK, Venkatesan S, Rajagopal A, Gokulakrishnan K, Balasubramanyam M, Mohan V, Manickam N
- KMID: 2546561
- J Lipid Atheroscler.
- 2023 Sep;12(3):290-306.
- doi: 10.12997/jla.2023.12.3.290
Objective: In previous research, we found that Sestrin2 has a strong association with plasma atherogenicity and combats the progression of atherogenesis by regulating the AMPK-mTOR pathway. Metformin, an activator of... -
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- Triglyceride-Rich Lipoproteins and Remnant Cholesterol in Cardiovascular Disease
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Heo JH, Jo SH
- KMID: 2546218
- J Korean Med Sci.
- 2023 Sep;38(38):e295.
- doi: 10.3346/jkms.2023.38.e295
Despite the well-established benefits of statin treatments in lowering low-density lipoprotein cholesterol (LDL-C), a significant residual risk for atherosclerotic cardiovascular disease (ASCVD) remains. Triglycerides (TGs) have long been recognized as... -
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- Coronary Physiology-Based Approaches for Plaque Vulnerability: Implications for Risk Prediction and Treatment Strategies
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Yang S, Koo BK
- KMID: 2545952
- Korean Circ J.
- 2023 Sep;53(9):581-593.
- doi: 10.4070/kcj.2023.0117
In the catheterization laboratory, the measurement of physiological indexes can help identify functionally significant lesions and has become one of the standard methods to guide treatment decision-making. Plaque vulnerability refers... -
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- Assessing the Practical Differences in LDL-C Estimates Calculated by Friedewald, Martin/Hopkins, or NIH Equation 2: An Observation CrossSectional Study
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Wang I, Rahman MH, Hou S, Lin HW
- KMID: 2546558
- J Lipid Atheroscler.
- 2023 Sep;12(3):252-266.
- doi: 10.12997/jla.2023.12.3.252
Objective: Low-density lipoprotein-cholesterol (LDL-C) remains a clinically important cholesterol target in primary prevention of atherosclerotic cardiovascular disease. The present study aimed to assess the practical differences among three equations utilized... -
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- Evaluation of Atherosclerotic Risk by Oxidative Contributors in Alcohol Use Disorder
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Senat A, Kabadayi-Sahin E, Sogut I, Duymaz T, Erel O
- KMID: 2545812
- Clin Psychopharmacol Neurosci.
- 2023 Aug;21(3):526-533.
- doi: 10.9758/cpn.22.1010
Objective: Alcohol Use Disorder (AUD) is a condition described as the inability to control or stop alcohol consumption. The patients with AUD have an increased risk of developing atherosclerosis-related diseases. The... -
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- Triglyceride-Glucose Index Predicts Future Atherosclerotic Cardiovascular Diseases: A 16-Year Follow-up in a Prospective, Community-Dwelling Cohort Study
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Moon JH, Kim Y, Oh TJ, Moon JH, Kwak SH, Park KS, Jang HC, Choi SH, Cho NH
- KMID: 2545273
- Endocrinol Metab.
- 2023 Aug;38(4):406-417.
- doi: 10.3803/EnM.2023.1703
Background: While the triglyceride-glucose (TyG) index is a measure of insulin resistance, its association with cardiovascular disease (CVD) has not been well elucidated. We evaluated the TyG index for prediction... -
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- A Review of Endovascular Treatment for Posterior Circulation Strokes
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Baik SH, Kim JY, Jung C
- KMID: 2543364
- Neurointervention.
- 2023 Jun;18(2):90-106.
- doi: 10.5469/neuroint.2023.00213
Mechanical thrombectomy for acute posterior circulation strokes (PCSs) is recommended based on evidence from anterior circulation strokes (ACSs). Two recent randomized controlled trials showed that endovascular treatment (EVT) leads to... -
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- Borderzone Infarcts and Recurrent Cerebrovascular Events in Symptomatic Intracranial Arterial Stenosis: A Systematic Review and Meta-Analysis
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Das S, Shu L, Morgan RJ, Shah A, Fayad FH, Goldstein ED, Chahien D, Maglinger B, Bokka SK, Owens C, Abbasi M, Kvernland A, Siegler JE, Grory BM, Nguyen TN, Furie K, Khatri P, Mistry E, Prabhakaran S, Liebeskind DS, Romano JG, Havenon Ad, Palaiodimou L, Tsivgoulis G, Yaghi S
- KMID: 2542473
- J Stroke.
- 2023 May;25(2):223-232.
- doi: 10.5853/jos.2023.00185
Background and Purpose Intracranial arterial stenosis (ICAS)-related stroke occurs due to three primary mechanisms with distinct infarct patterns: (1) borderzone infarcts (BZI) due to impaired distal perfusion, (2) territorial infarcts... -
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- Benefits and Harms of COVID-19 Vaccines in Cardiovascular Disease: A Comprehensive Review
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Chen CY, Su TC
- KMID: 2542817
- J Lipid Atheroscler.
- 2023 May;12(2):119-131.
- doi: 10.12997/jla.2023.12.2.119
Patients with a history of cardiovascular disease (CVD) who contract coronavirus disease 2019 (COVID-19) tend to have a worse prognosis and more severe cardiovascular side effects. COVID-19 vaccines, which are intended... -
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- Roles of Vascular Smooth Muscle Cells in Atherosclerotic Calcification
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Woo SH, Kim DY, Choi JH
- KMID: 2542816
- J Lipid Atheroscler.
- 2023 May;12(2):106-118.
- doi: 10.12997/jla.2023.12.2.106
The accumulation of calcium in atherosclerotic plaques is a prominent feature of advanced atherosclerosis, and it has a strong positive correlation with the total burden of atherosclerosis. Atherosclerotic calcification usually... -
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- The Ratio of Estimated Glomerular Filtration Rate Based on Cystatin C and Creatinine Reflecting Cardiovascular Risk in Diabetic Patients
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Khang AR, Lee MJ, Yi D, Kang YH
- KMID: 2542518
- Diabetes Metab J.
- 2023 May;47(3):415-425.
- doi: 10.4093/dmj.2022.0177
Background: The ratio of estimated glomerular filtration rate (eGFR) based on cystatin C and creatinine (eGFRcystatin C/eGFRcreatinine ratio) is related to accumulating atherosclerosis-promoting proteins and increased mortality in several cohorts. Methods:... -
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- Comparison of health indicators and lifestyle according to atherogenic index of plasma in Korean adults in their 20s and 30s
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Hwang B, Yang YJ
- KMID: 2542270
- J Nutr Health.
- 2023 Apr;56(2):168-183.
- doi: 10.4163/jnh.2023.56.2.168
Purpose: Cardiovascular disease is one of the major causes of death not only in Korea but also worldwide. Atherogenic index of plasma (AIP) has been extensively investigated, but studies on... -
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- Association between Aortic Calcification Burden and the Severity of Erectile Dysfunction in Men Undergoing Dialysis: A Cross-Sectional Study
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Fujita N, Hatakeyama S, Momota M, Tobisawa Y, Yoneyama T, Okamoto T, Yamamoto H, Yoneyama T, Hashimoto Y, Yoshikawa K, Ohyama C
- KMID: 2540969
- World J Mens Health.
- 2023 Apr;41(2):373-381.
- doi: 10.5534/wjmh.210230
Purpose Accelerated atherosclerosis is a major complication in patients with end-stage renal disease and it plays an important role in the pathogenesis of erectile dysfunction (ED). However, the association between aortic... -
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- Relationship between Body Composition and Arterial Stiffness in Korean Adults
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Jang HJ, Koh HM, Jang JY, Lee HJ, Moon JS, Ji JM, Lee 1 A
- KMID: 2540642
- Korean J Fam Pract.
- 2023 Mar;13(1):23-30.
- doi: 10.21215/kjfp.2023.13.1.23
Background: This study is aimed to evaluate the relationship between sarcopenic obesity and atherosclerosis in Korean adults. Methods: We studied 7,177 participants who visited the health promotion center of a university... -
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- Non-Alcoholic Fatty Liver Disease with Sarcopenia and Carotid Plaque Progression Risk in Patients with Type 2 Diabetes Mellitus
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Cho Y, Park HS, Huh BW, Lee Yh, Seo SH, Seo DH, Ahn SH, Hong S, Kim SH
- KMID: 2540520
- Diabetes Metab J.
- 2023 Mar;47(2):232-241.
- doi: 10.4093/dmj.2021.0355
Background: We aimed to evaluate whether non-alcoholic fatty liver disease (NAFLD) with or without sarcopenia is associated with progression of carotid atherosclerosis in patients with type 2 diabetes mellitus (T2DM). Methods:... -
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- Wall Shear Stress Associated with Stroke Occurrence and Mechanisms in Middle Cerebral Artery Atherosclerosis
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Woo HG, Kim HG, Lee KM, Ha SH, Jo H, Heo SH, Chang Di, Liebeskind DS, Kim BJ
- KMID: 2539066
- J Stroke.
- 2023 Jan;25(1):132-140.
- doi: 10.5853/jos.2022.02754
Background and Purpose Various mechanisms are involved in the etiology of stroke caused by atherosclerosis of the middle cerebral artery (MCA). Here, we compared differences in plaque nature and hemodynamic... -
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