Korean J Med.  1998 Mar;54(3):355-362.

Factors Contributing to Mortality in Chronic Hemodialysis Patients

Affiliations
  • 1Department of Internal Medicine, Seoul Red Cross Hospital.
  • 2Department of Internal Medicine, Kangbook Samsung Hospital.
  • 3Department of Internal Medicine, Annam Hospital; Kuro Hospital.
  • 4Department of Internal Medicine, Sungnam Jungang Hospital.
  • 5Department of Internal Medicine, Seoul Adventist Hospital.
  • 6Department of Internal Medicine, Cheongju Rira Hospital.
  • 7Department of Internal Medicine, Hallym Hospital.

Abstract

BACKGROUND: Several factors have been influenced to mortality of patients with end-stage renal disease treated with hemodialysis. We performed this study to evaluate the factors influencing to mortality in chronic hemodialysis patients in eight hemodialysis centers. METHOD: We analyzed retrospectively the demo graphic characteristics, risk stratification, Karnofsky scale, regularly tested laboratory finding(CBC, Blood chem istry), hospitalization rate, and gross mortality among 150 patients from June, 1994 to June 1996.
RESULTS
1) A total of 150 patients were enrolled, male 91 and female 59 and mean age was about 53 years. 43 patients had diabetes and 107 patients had nondiabetes. The mean duration of hemodialysis was 48.2+/-24.7 months(range, 9-123months). 2) 82 patients(54.7%) required hospitalization during the 2 year follow-up period and the most common cause of hospitalization was cardiovascular disease. 3) A total of 43 patients(28.7%) had been died during the 2 year follow-up period and the most common cause of death was cerebrovascular disease. 4) In univariate analysis, advancing age, Karnofsky scale(<80 points), diabetic nephropathy as the underlying cause of ESRD, comorbid illness, high risk group in risk stratification, total HD duration, HD length per week, low serum albumin and creatitine concentration were all asso ciated with significantly increased risk of death. In multi variate analysis, diabetic nephropathy as the underlying cause of ESRD and low serum albumin concentration were more highly associated with death probability.
CONCLUSION
We conclude that diabetic nephropathy as underlying cause of ESRD and serum albumin concen tration are more important elements in determining pa tient mortality.

Keyword

Chronic hemodialysis; Mortality; Serum albumin concentration; Diabetic nephropathy
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