Korean J Med.  2010 Feb;78(2):222-225.

A case of exophytic pedunculated gastrointestinal stromal tumor with cystic changes

• Kim SW
• Cha SC
• Cho YJ
• Park HK
• Park SK
• Kang HJ

Abstract

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, and cystic changes are commonly observed. However, there have been few reports of cases of exophytic pedunculated GIST with cystic changes. Here, we report a 45-year-old man who presented with a palpable mass in the left upper quadrant of the abdomen. The mucosal folds were endoscopically abnormal, but there was no mucosal lesion. Computed tomography demonstrated a large, low-density cystic lesion surrounding an enhanced nodule in the greater curvature of the gastric body, and there was no tumor infiltration to other organs. The patient underwent hemigastrectomy and the lesion was shown to be an exophytic pedunculated cystic tumor. Histopathological examination showed epithelioid cells with marked hemorrhaging. Immunohistochemical examination indicated that most of the tumor cell cytoplasm was positive for the c-kit protein (CD117) and CD34. The tumor was diagnosed as an exophytic pedunculated GIST of the stomach with cystic changes.

Keyword

Gastrointestinal stromal tumor (GIST); Exophytic; Pedunculated; Cyst

MeSH Terms

Abdomen
Cytoplasm
Epithelioid Cells
Gastrointestinal Stromal Tumors
Gastrointestinal Tract
Humans
Middle Aged
Proto-Oncogene Proteins c-kit
Stomach
Proto-Oncogene Proteins c-kit