Korean J Otolaryngol-Head Neck Surg.  2002 Sep;45(9):926-929.

A Case of Multifocal Mucosa-associated Lymphoid Tissue Lymphoma Involving Ethmoid Sinus, Hard Palate and Cheek

• Rhyoo C
• Jung MK
• Kim JH
• Lee HK

Abstract

Mucosa-associated lymphoid tissue (MALT) is a specialized form of lymphiod tissue that may be acquired at sites in response to chronic inflammation. MALT lymphoma is a type of low-grade, B-cell lymphoma within the spectrum of non-Hodgkin's extranodal lymphomas, and may arise within several sites in the head and neck. Because of the differences in the natural history, prognosis, and therapy of MALT lymphoma and other lymphomas, the immunohistochemical and molecular biology studies should be considered in the diagnosis of MALT lymphoma in cases where atypical lymphoid infiltrates into the head and neck. We present a case of advanced staged multifocal MALT lymphoma, which has disseminated into the bone marrow, involving mucosal sites of the ethmoid sinus, hard palate and cheek, but not the gastrointestinal tract, with a review of relevant literature.

Keyword

Lymphoma, mucosa-associated lymphoid tissue; Immunohistochemistry

MeSH Terms

Bone Marrow
Cheek*
Diagnosis
Ethmoid Sinus*
Gastrointestinal Tract
Head
Immunohistochemistry
Inflammation
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell
Lymphoma, B-Cell, Marginal Zone*
Molecular Biology
Natural History
Neck
Palate, Hard*
Prognosis