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Natural History of Chronic Urticaria in Korea

Chung BY, Um JY, Kang SY, Kim HO, Park CW

BACKGROUND: Data on the natural history and prognostic variables of chronic urticaria (CU) are rare and information about spontaneous remission of CU is limited. OBJECTIVE: This study evaluated the natural history...
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Understanding the importance of cerebrovascular involvement in Kawasaki disease

Yeom JS, Cho JY, Woo HO

Kawasaki disease (KD) is a systemic vasculitis in infants and young children. However, its natural history has not been fully elucidated because the first case was reported in the late...
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Stiff-Person Syndrome: Diagnostic Difficulty

Lee JK, Kang C, Kim SB, An BK, Lee GS

Stiff-person syndrome is a rare disorder, and the natural history of the syndrome has not been completely ascertained. The symptoms range from mild to severe and can progress over time:...
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Two Cases of Radiologically Isolated Syndrome: First Case Report in Korea

Im K, Sunwoo JS, Kwon KY, Lee KB, Ahn MY, Roh H

With increasing sensitivity, availability, and use of magnetic resonance imaging (MRI) in the past three decades, there is also an increase in incidental abnormal findings. The most common findings of...
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Understanding the Natural History of Bicuspid Aortic Valve: Are We Close to Understanding It?

Lee SP

No abstract available.
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Growth Pattern and Prognostic Factors of Untreated Nonfunctioning Pituitary Adenomas

Hwang K, Kwon T, Park J, Joo JD, Han JH, Oh CW, Kim CY

OBJECTIVE: Pituitary adenomas (PAs) are often detected as incidental findings. However, the natural history remains unclear. The objective of this study was to evaluate the natural history and growth pattern...
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A Case of Asymptomatic Multiple Endocrine Neoplasia Type I with Thymic Carcinoid

Park SK, Lee MW, Han IS, Park YJ, Han SY, Park JW, Lee BE, Kim GH, Kim SS

Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal dominant hereditary disorder caused by germline mutation of the MEN1 gene. It is characterized by tumors of the anterior pituitary...
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Anal Adenocarcinoma Can Masquerade as Chronic Anal Fistula in Asians

Leong FQ, Chan DK, Tan KK

PURPOSE: Perianal adenocarcinoma arising from a chronic anorectal fistula is a rare condition for which the natural history and optimal management are not well established. For that reason, we conducted...
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Anterior Bone Loss in Cervical Disc Arthroplasty

Kieser DC, Cawley DT, Fujishiro , Tavolaro C, Mazas S, Boissiere , Obeid I, Pointillart V, Vital JM, Gille O

STUDY DESIGN: Retrospective, longitudinal observational study. PURPOSE: To describe the natural history of anterior bone loss (ABL) in cervical disc arthroplasty (CDA) and introduce a classification system for its assessment. OVERVIEW OF...
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Natural History Data in Symptomatic Severe Aortic Stenosis Alerts Cardiologists to the Dangers of No Action

Lee HJ, Kim HK

No abstract available.
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Treatment response and disease progression

Holford N

This tutorial defines the concepts of disease progression in the context of clinical pharmacology. Disease progression describes the natural history of disease, such as pain, or biomarker of drug response,...
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Long Term Efficacy of Antiviral Therapy: Mortality and Incidence of Hepatocellular Carcinoma

Lee HW

Multiple studies have shown that oral antiviral therapies reduced the incidence of hepatocellular carcinoma (HCC) and improved the survival of patients with chronic hepatitis B when compared with that of...
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Natural History and Treatment Indications of Chronic Hepatitis B

Sinn DH

HBV is the most common etiology of both liver cirrhosis and hepatocellular carcinoma in Korea. Despite much progress made, the currently available antiviral therapies cannot eradicate or eliminate this virus....
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Characteristics and Clinical Course of Fusiform Middle Cerebral Artery Aneurysms According to Location, Size, and Configuration

Seo D, Lee SU, Oh CW, Kwon OK, Ban SP, Kim T, Byoun HS, Kim YD, Lee Y, Won YD, Bang JS

OBJECTIVE: To analyze the angiographic features and clinical course, including treatment outcomes and the natural course, of fusiform middle cerebral artery aneurysms (FMCAAs) according to their location, size, and configuration. METHODS:...
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New Perspectives in Pediatric Nonalcoholic Fatty Liver Disease: Epidemiology, Genetics, Diagnosis, and Natural History

Ko JS

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in children. The global prevalence of pediatric NAFLD from general populations is 7.6%. In obese children,...
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Coronary-to-Pulmonary Artery Fistula in Adults: Natural History and Management Strategies

Kim H, Beck KS, Choe YH, Jung JI

OBJECTIVE: To evaluate the natural course of coronary-to-pulmonary artery fistula (CPAF) detected on coronary computed tomography angiography (CCTA) and to propose potential treatment strategies. MATERIALS AND METHODS: In this retrospective multicenter...
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Clinical Features and Treatment Outcomes of Immune Thrombocytopenic Purpura in Infants: A Single Center Retrospective Study

Sohn SJ, Park KM, Yang EJ, Lim YT

BACKGROUND: Immune thrombocytopenic purpura (ITP) in children less than one year of age is less well characterized compared to ITP in toddlers and school-age children. Since children of different ages...
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Continued loss of asthma control following epidemic thunderstorm asthma

Foo CT, Yee EL, Young A, Denton E, Hew M, O'Hehir RE, Radhakrishna N, Matthews S, Conron M, Harun NS, Lachapelle P, Douglass J, Irving L, Lee J, Stevenson , McDonald C, Langton D, Banks C, Thien F

BACKGROUND: Epidemic thunderstorm asthma (ETSA) severely affected Melbourne, Australia in November 2016. There is scant literature on the natural history of individuals affected by ETSA. OBJECTIVE: A multicentre 12-month prospective observational...
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Diagnosis and Management of Diabetic Peripheral Neuropathy

Moon SS

Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and is diagnosed as the presence of symptoms and/or signs of peripheral nerve dysfunction in people with...
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Role of the Duodenum in the Pathogenesis of Functional Dyspepsia: A Paradigm Shift

Jung HK, Talley NJ

  • KMID: 2417379
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):345-354.
  • doi: 10.5056/jnm18060
Functional dyspepsia (FD) is a common disorder characterized by chronic epigastric pain or burning, or bothersome postprandial fullness or early satiation, without a definitive organic cause. The pathogenesis of FD...
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