J Korean Med Assoc.  2009 Jan;52(1):30-40. 10.5124/jkma.2009.52.1.30.

Interstitial Lung Diseases in Collagen Vascular Diseases

• Jeong SH

• KMID: 2137731
• DOI: http://doi.org/10.5124/jkma.2009.52.1.30

Abstract

Different types of interstitial lung diseases (ILDs) develop in collagen vascular diseases (CVDs) such as scleroderma, rheumatoid arthritis, systemic lupus erythematosus, dermatopolymyositis, Sjogren's syndrome, and mixed connective tissue disease. These CVDs represent various histological patterns, including usual interstitial pneumonia, desquamative interstitial pneumonia, nonspecific interstitial pneumonia, bronchiolitis obliterance organizing pneumonia, diffuse alveolar damage, and bronchiolitis. The clinical presentations, prognosis, and response to treatment vary depending on the underlying CVDs, as well as histological patterns of ILDs. In general, the prognosis and survival rate of ILDs in CVDs are better than idiopathic ILDs. Optimal treatment also varies depending on the type of CVDs and the presence of interstitial lung disease, although in many cases, a combination of corticosteroids and cytotoxic drugs are given.

Keyword

Collagen vascular disease; Interstitial lung disease; Fibrosis

MeSH Terms

Adrenal Cortex Hormones
Arthritis, Rheumatoid
Bronchiolitis
Collagen
Dermatomyositis
Fibrosis
Idiopathic Pulmonary Fibrosis
Lung Diseases, Interstitial
Lupus Erythematosus, Systemic
Mixed Connective Tissue Disease
Pneumonia
Prognosis
Sjogren's Syndrome
Survival Rate
Vascular Diseases
Adrenal Cortex Hormones
Collagen