Infect Chemother.  2005 Dec;37(6):359-363.

Candida guilliermondii Endophthalmitis in a Patient with Mixed Gastrointestinal Stromal Tumor and Stomach Adenocarcinoma

• Ahn KS
• Kho JW
• Park JH
• Lee K
• Park SN
• Lee HJ
• Jung JH
• Jung MH

Abstract

Candida is the most common etiologic agent causing endogenous endophthalmitis resulting due to hematogenous spread from a remote primary focus. Risk factors for the infection include intravenous drug use, hyperalimentation, surgery, malignancy, diabetes, neutropenia, and the use of broad- spectrum antibiotics and immunosuppressive agents, especially corticosteroids. The outcome of candida endophthalmitis is disappointing. One main problem in the management of this infection is that early diagnosis is difficult. Thus, treatment may be delayed and this which often leads to a poor outcome. Candida endophthalmitis, particularly candida guilliermondii endophthalmitis, is extremely rare, although it is becoming more common as the number of chronically debilitated patients and the use of invasive procedures increase. It is an ophthalmologic emergency and commonly takes a tragic course. Therefore, early suspicion and aggressive management are imperative to prevent visual loss. The authors report a case of candida endophthalmitis caused by Candida guilliermondii in a 65-year-old man with mixed gastrointestinal stromal tumor(GIST) and stomach adenocarcinoma.

Keyword

Candida endophthalmitis; Candida guilliermondii; Adenocarcinoma

MeSH Terms

Adenocarcinoma*
Adrenal Cortex Hormones
Aged
Anti-Bacterial Agents
Candida*
Early Diagnosis
Emergencies
Endophthalmitis*
Gastrointestinal Stromal Tumors*
Humans
Immunosuppressive Agents
Neutropenia
Risk Factors
Stomach*
Adrenal Cortex Hormones
Anti-Bacterial Agents
Immunosuppressive Agents