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Selection Strategies and Practical Application of BRAF V600E-Mutated Non–Small Cell Lung Carcinoma

Hwang I, Choi YL, Lee H, Hwang S, Lee B, Yang H, Chelakkot C, Han J

Purpose The incidence of BRAF V600E mutation in non-small cell lung carcinoma (NSCLC) is lower than 2%, which poses difficulties in finding legitimate patients for targeted therapy. We investigated the predictive...
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Histologic Changes in Non–Small Cell Lung Cancer under Various Treatments: A Comparison of Histology and Mutation Status in Serial Samples

Woo CG, Son SM, Lee HC, Han HS, Lee KH, Kim D, Kim EG, Lee OJ

Purpose Histologic change is a resistant mechanism in lung cancer. The most common histological change is the switch from adenocarcinoma (AdenoCa) to small cell carcinoma (SCC) against to tyrosine kinase inhibitors...
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Should transanal total mesorectal excision be implemented in medium-sized colorectal unit? technical and oncological outcome

Ho Mf, Ng DCK, Lee JFy, Ng SSm

Purpose: This study was performed to evaluate the outcome of implementation of transanal total mesorectal excision (TaTME) for low rectal cancer in a regional hospital and in comparison to laparoscopic...
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A Case of Carcinoma with Sebaceous Differentiation arising in the Patient who was Treated with Parotid Gland Adenocarcinoma

Park S, Yun JH, Go YJ, Jung SY

Sebaceous carcinoma is extremely rare in the parotid gland. Recently, we experienced a case of carcinoma with sebaceous differentiation arising from the parotid gland in patient who was diagnosed as...
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Epidemiology of early esophageal adenocarcinoma

Hang TVP, Spiritos Z, Gamboa AM, Chen Z, Force S, Patel V, Chawla S, Keilin S, Saba NF, El-Rayes B, Cai Q, Willingham FF

Background/Aims: Endoscopic resection has become the preferred treatment approach for select early esophageal adenocarcinoma (EAC); however, the epidemiology of early stage disease has not been well defined. Methods: Surveillance Epidemiology and...
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The clinical outcomes of second-line chemotherapy in patients with advanced pancreatic cancer: a retrospective study

Jung Hy, Lee EM

Background: Despite recent advances in first-line chemotherapy for advanced pancreatic cancer, standard treatment after the failure of initial chemotherapy has not been established. Hence, we aimed to retrospectively analyze the...
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The Clinical Outcomes of Different First-Line EGFR-TKIs Plus Bevacizumab in Advanced EGFR-Mutant Lung Adenocarcinoma

Huang YH, Hsu KH, Chin CS, Tseng JS, Yang TY, Chen KC, Su KY, Yu SL, Chen JJ, Chang GC

Purpose The aim of this study was to investigate the efficacy of various epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) plus bevacizumab in advanced EGFR-mutant lung adenocarcinoma patients. Materials and Methods From...
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Primary Mucinous Adenocarcinoma of the Lower Eyelid

Choi YS, Jung DH, Chi M

Purpose: We report a case of a primary mucinous adenocarcinoma of the lower eyelid diagnosed in patient with a painless mass. Case summary: A 62-year-old male visited our clinic with a...
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Dome-type carcinoma of the rectum mimicking a submucosal tumor: a case report and literature review

Noh BJ, Park SJ, Jang JY, Kim YW

Dome-type carcinoma (DC) has been recognized as a rare variant of adenocarcinoma, which arises in gutassociated lymphoid tissue. It has a specific morphologic feature of a dome-like protrusion associated with...
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Incidence and predictive factors for recurrent clear cell ovarian carcinoma: results from a single center in Thailand

Hemman W, Rattanaburi A

Objective We aimed to study the incidence and predictive factors of recurrent clear cell ovarian carcinoma (CCC) and evaluate the oncological outcomes after recurrence. Methods This was a retrospective study of 134 CCC...
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Prognosis for Pneumonic-Type Invasive Mucinous Adenocarcinoma in a Single Lobe on CT: Is It Reasonable to Designate It as Clinical T3?

Kim W, Lee SM, Lee JB, Seo JB, Kim HK, Kim J, Lee HY

Objective: To compare pneumonic-type invasive mucinous adenocarcinoma (pIMA) confined to a single lobe with clinical T2, T3, and T4 stage lung cancer without pathological node metastasis regarding survival after curative...
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Colorectal adenocarcinoma with enteroblastic differentiation: diagnostic challenges of a rare case encountered in clinical practice

Abada E, Anaya IC, Abada O, Lebbos A, Beydoun R

Colorectal adenocarcinoma with enteroblastic differentiation (CAED) is a rare subtype of colonic adenocarcinoma characterized by increased α-fetoprotein (AFP) production and the expression of at least one enteroblastic marker including AFP,...
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Extremely well-differentiated adenocarcinoma of the stomach: diagnostic pitfalls in endoscopic biopsy

Lee J, Lee IS, Ahn JY, Park YS, Kim J

Background: Extremely well-differentiated adenocarcinoma (EWDA) is a deceptively bland-looking adenocarcinoma of the stomach. It often causes diagnostic problems, especially in endoscopic biopsy samples. To better recognize this deceptively bland lesion,...
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Anti-Hu Antibody-Mediated Myelopathy Associated with Gastric Adenocarcinoma

Park KS, Kim JJ, Shin DH, Shin JH

Anti-Hu antibody causes paraneoplastic syndrome of the nervous system. Most of the anti-Hu antibodies are found with small cell lung cancer, but can rarely be found with other cancers such...
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An Adenocarcinoma Associated with Bilateral, Diffuse, Uveal Melanocytic Proliferation

Chung W, Kim SH, Choi Y, Choi SK, Lee JJ, Park SW, Byon IS

Purpose: We report bilateral, diffuse, uveal melanocytic proliferation caused by a stomach adenocarcinoma. Case summary: A 78-year-old male complained of visual impairment 3 months in duration. He had diabetes and had...
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Relationship between 18F-FDG PET/CT Semi-Quantitative Parameters and International Association for the Study of Lung Cancer, American Thoracic Society/European Respiratory Society Classification in Lung Adenocarcinomas

Bu L, Tu N, Wang K, Zhou Y, Xie X, Han X, Lin H, Feng H

Objective: To investigate the relationship between 18F-FDG PET/CT semi-quantitative parameters and the International Association for the Study of Lung Cancer, American Thoracic Society/European Respiratory Society (IASLC/ATS/ERS) histopathologic classification, including histological...
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Endoscopic Submucosal Dissection for Superficial Barrett’s Neoplasia in Korea: a Single-Center Experience

Joo DC, Kim GH, Lee BE, Lee MW, Baek DH, Song GA, Lee S, Park DY

Purpose: While the incidence of Barrett’s neoplasia has been increasing in Western countries, the disease remains rare in Asian countries. Therefore, very few studies have investigated the endoscopic treatment for...
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Epstein-Barr Virus-associated Mixed Lymphoepithelioma-like Carcinoma and Adenocarcinoma of the Gall Bladder: An Unusual Entity

Jain N, Goyal S, Sakhuja P, Saluja S

Schmincke described lymphoepithelioma as an undifferentiated carcinoma with abundant lymphoid stroma in the nasopharynx. Tumors with a similar histomorphology in extrapharyngeal areas have been referred to as lymphoepithelioma-like carcinoma (LELC)....
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SMARCA4/BRG1 protein-deficient thoracic tumors dictate re-examination of small biopsy reporting in non–small cell lung cancer

Mehta A, Bansal D, Tripathi R, Jajodia A

Background: SMARCA4/BRG1 protein–deficient lung adenocarcinomas and thoracic sarcoma are recently described entities that lack distinctive histological features, transcription termination factor 1 (TTF1) reactivity, and actionable driver mutations. The current diagnostic...
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How to Combine Diffusion-Weighted and T2-Weighted Imaging for MRI Assessment of Pathologic Complete Response to Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer?

Jang JK, Lee Cm, Park SH, Kim JH, Kim J, Lim SB, Yu CS, Kim JC

Objective: Adequate methods of combining T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) to assess complete response (CR) to chemoradiotherapy (CRT) for rectal cancer are obscure. We aimed to determine an...
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