Korean J Dermatol.
2015 Nov;53(9):717-721.
Disseminated Papules and Pustules with Lymphadenitis after Bacillus Calmette-Guerin Vaccination in an Infant
- Affiliations
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- 1Department of Dermatology, School of Medicine, Keimyung University, Daegu, Korea. franzes@dsmc.or.kr
Abstract
- Bacillus Calmette-Guerin (BCG) is the live attenuated strain of Mycobacterium bovis that produces resistance to tuberculosis (TB) infection. BCG vaccination may induce various dermatologic complications. A 3-month-old infant who had BCG vaccination a month after birth developed erythematous papules and pustules on the trunk and both extremities. The biopsy from the left leg showed a granulomatous lesion. Acid fast staining and nested TB polymerase chain reaction (TB-PCR) were negative. A tuberculin skin test and an interferon-gamma release assay also revealed a negative result. A painful mass was noted on the left axillary area with a positive-nested TB-PCR and surgical excision was performed. The skin eruptions improved after 2 months of anti-tuberculosis medication. Herein, we report a case of disseminated papules and pustules with lymphadenitis after BCG vaccination.
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