J Korean Surg Soc.  2009 May;76(5):273-278. 10.4174/jkss.2009.76.5.273.

Usefulness of the Sequential Organ Failure Assessment (SOFA) Score in Patients with Sepsis due to Intra-abdominal Infection

• Choi WH
• Hwang SY
• Jun SY
• Choi YC
• Lee EH
• Yu WS

• KMID: 2096546
• DOI: http://doi.org/10.4174/jkss.2009.76.5.273

Abstract

PURPOSE
To determine the usefulness of the Sequential Organ Failure Assessment (SOFA) score for prediction of mortality in operated patients with sepsis due to intra-abdominal infection. METHODS: Eighty-eight septic patients operated on from January 2004 to June 2008 were evaluated retrospectively. The SOFA scores were measured four times in each patient: initial score, post-op (post-operation) score, POD1 (first post-operative day) score, and POD2 (second post-operative day) score. The maximum score and mean score were obtained from these measurements. These scores were compared between groups of patients classified by mortality. D scores (D0, D1, D2) reflecting the differences between subsequent scores were compared between the surviving group and deceased group according to re-operation. RESULTS: The initial, post-op, POD1, POD2, maximum, and mean scores showed statistically significant differences between the surviving group and deceased group. D1 and D2 showed statistically significant differences between surviving group and deceased group. CONCLUSION: The sequential measurement of SOFA score is a useful prediction system for patients with sepsis due to intra-abdominal infection.

Keyword

Sepsis; Intra-abdominal; Infection; Mortality

MeSH Terms

Humans
Intraabdominal Infections
Retrospective Studies
Sepsis

Figure

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  Fig. 1 The relationship between delta sequential organ failure assessment (SOFA) score and mortality according to re-operation. In patients not undergoing re-operation (A), the sequential changes of delta SOFA scores between live and dead differed significantly (P=0.021). The former had a gradual reducing trend, while the latter had an abrupt increasing trend. In patients undergoing re-operation (B), however, both those sequential changes did not differ and had downward directions together.

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  Fig. 2 The interaction between the sequential changes of each delta sequential organ failure assessment (SOFA) scores and survival on condition of adjustment by re-operation. Live had a gradual reducing trend of delta SOFA scores while dead had an increasing trend (P=0.035).

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