Korean J Dermatol.
2003 Jul;41(7):932-935.
A Case of Generalized Subcutaneous Fat Necrosis of Newborn
- Affiliations
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- 1Department of Dermatology, Eulji Hospital Eulji Medical College, Korea.
- 2Department of Pediatrics, Eulji Hospital Eulji Medical College, Korea.
- 3Department of Pathology, Collage of Medicine, Chung-Ang University, korea.
Abstract
- Subcutaneous fat necrosis of newborn is an uncommon disorder characterized by firm subcutaneous plaques and nodules usually appearing shortly after birth. A female newborn with brain death developed diffuse hardening of trunk, extremity, cheek and buttock in the first 5 weeks of the life. A clinical diagnosis of sclerema neonatorum was made. But histologic examination revealed patchy areas of fat necrosis with crystallization, infiltration of histologic cells and several multinucleated giant cells containing needle-shaped clefts. Calcium deposits were also demonstrated within the necrotic area. So, we diagnosed this case as subcutaneous fat necrosis of newborn with generalized hardening of the skin.
