Korean J Med.
2006 Sep;71(3):309-315.
A case of ectopic adrenocorticotropic hormone syndrome with olfactory neuroblastoma
- Affiliations
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- 1Department of Internal Medicine, College of Medicine Seoul National University, Seoul, Korea. ymchomd@snu.ac.kr
Abstract
- We here present the case of a 37-year-old woman who suffered from adrenocorticotrophic hormone (ACTH)-dependent Cushing's syndrome due to an olfactory neuroblastoma. The patient's clinical course was complicated by co-infection with cytomegalovirus and Pneumocystis jirovechi, which improved with appropriate antimicrobial therapy and suppression of endogenous steroidogenesis with ketoconazole and octreotide. Radiation to the mass in the nasal cavity resulted in reduction of tumor size and remission of the Cushing's syndrome. This is the first report of the ectopic ACTH syndrome resulting from olfactory neuroblastoma in Korea.
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