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Impact of COVID-19 and Associated Preventive Measures on Cardiometabolic Risk Factors in South Korea

Sohn M, Koo BK, Yoon HI, Song KH, Kim ES, Kim HB, Lim S

Background: During the coronavirus disease 2019 (COVID-19) pandemic, preventive measures mandated by government policies have included the closure of exercise facilities and movement restriction, which can lead to an unhealthy...
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Non-invasive vs. Invasive Functional Tests after Coronary Stent Implantation

Hwang D, Koo BK

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Coronary Artery Lumen Segmentation Using Location– Adaptive Threshold in Coronary Computed Tomographic Angiography: A Proof-of-Concept

Shin CI, Park SJ, Kim JH, Yoon YE, Park EA, Koo BK, Lee W

Objective: To compare the lumen parameters measured by the location-adaptive threshold method (LATM), in which the inter- and intra-scan attenuation variabilities of coronary computed tomographic angiography (CCTA) were corrected, and...
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Letter: Effects of 6 Months of Dapagliflozin Treatment on Metabolic Profile and Endothelial Cell Dysfunction for Obese Type 2 Diabetes Mellitus Patients without Atherosclerotic Cardiovascular Disease (J Obes Metab Syndr 2020;29:215-21)

Koo BK

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Physiologic Assessment after Coronary Stent Implantation

Hwang D, Yang S, Zhang J, Koo BK

The presence of myocardial ischemia is a prerequisite for the benefit of coronary revascularization. In the cardiac catheterization laboratory, fractional flow reserve and non-hyperemic pressure ratios are used to define...
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Long-term efficacy of vasodilating β-blocker in patients with acute myocardial infarction: nationwide multicenter prospective registry

Chung J, Han JK, Yang HM, Park KW, Kang HJ, Koo BK, Jeong MH, Kim HS, on behalf of investigators for Korea Acute Myocardial Infarction Registry (KAMIR)

Background/Aims: Long-term benefit of vasodilating β-blockers is unknown. This study aimed to investigate the long-term benefit of vasodilating β-blockers over conventional β-blockers in patients with acute myocardial infarction (AMI). Methods: Using...
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Progression of ascending aortopathy may not occur after transcatheter aortic valve replacement in severe bicuspid aortic stenosis

Jung JH, Kim HK, Park JB, Lee SP, Koo BK, Kim YJ, Kim HS, Sohn DW

Background/Aims: We evaluated changes in the ascending aorta dimension post-transcatheter aortic valve replacement (TAVR) in bicuspid aortic valve (BiAV) and tricuspid aortic valve (TAV) patients. Methods: Patients with severe aortic stenosis...
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Association of Quantitative Flow Ratio with Lesion Severity and Its Ability to Discriminate Myocardial Ischemia

Dai N, Hwang D, Lee JM, Zhang J, Tong Y, Jeon KH, Paeng JC, Cheon GJ, Koo BK, Ge J

Background and Objectives: Quantitative flow ratio (QFR) is an angiography-based technique for functional assessment of coronary artery stenosis. This study investigated the response of QFR to different degree of stenosis...
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Metformin Preserves Peripheral Nerve Damage with Comparable Effects to Alpha Lipoic Acid in Streptozotocin/High-Fat Diet Induced Diabetic Rats (Diabetes Metab J 2020;44:842-53)

Koo BK

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Hypertriglyceridemia Is an Independent Risk Factor for Cardiovascular Diseases in Korean Adults Aged 30–49 Years: a Nationwide Population-Based Study

Koo BK, Park S, Han KD, Moon MK

Objective: This study was conducted to estimate the incidence of cardiovascular disease (CVD) independently from low-density lipoprotein (LDL) cholesterol according to triglyceride (TG) levels in young adults. Methods: Subjects aged 30–49...
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Acute ST-elevation myocardial infarction due to prosthetic valve endocarditis after transcatheter aortic valve implantation

Cho JH, Han JK, Yang HM, Koo BK, Kim HS

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Glucose Metabolism in Pregnant Women with Normal Glucose Tolerance

Koo BK

Insulin resistance increases from conception into late pregnancy in women with normal glucose tolerance as well as women with gestational diabetes. Increasing insulin resistance during pregnancy permits adequate supply of...
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Proper Management of People with Obesity during the COVID-19 Pandemic

Lim S, Shin SM, Nam GE, Jung CH, Koo BK

Since December 2019, countries around the world have been struggling with a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Case series have reported that people with obesity experience...
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Glove-Wall System for Respiratory Specimen Collection and COVID-19 Mass Screening

Koo BK, Bang JH, Kim SY, Kim EJ, Park SW

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Validation of Risk Prediction Models for Atherosclerotic Cardiovascular Disease in a Prospective Korean Community-Based Cohort

Bae JH, Moon MK, Oh S, Koo BK, Cho NH, Lee MK

BackgroundTo investigate the performance of the 2013 American College of Cardiology/American Heart Association Pooled Cohort Equations (PCE) in a large, prospective, community-based cohort in Korea and to compare it with...
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Comparison of Exercise Performance and Clinical Outcome Between Functional Complete and Incomplete Revascularization

Kim J, Lee JM, Choi SH, Choi KH, Park TK, Park SJ, Yang JH, Song YB, Hahn JY, Jang MJ, Koo BK, Gwon HC

BACKGROUND AND OBJECTIVES: Although percutaneous coronary intervention (PCI) is recommended to improve symptoms in patients with stable ischemic heart disease (SIHD), improvement of exercise performance is controversial. This study aimed...
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Associations of Perirenal Fat Thickness with Renal and Systemic Calcified Atherosclerosis

Koo BK, Denenberg , Wright CM, Criqui MH, Allison MA

BACKGROUND: We investigated associations between perirenal fat thickness and atherosclerotic calcification in six different vascular beds. METHODS: Using a community-based cohort (n=3,919), perirenal fat thickness was estimated from computed tomography scans....
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Long-term Patient Prognostication by Coronary Flow Reserve and Index of Microcirculatory Resistance: International Registry of Comprehensive Physiologic Assessment

Lee JM, Choi KH, Doh JH, Nam CW, Shin ES, Hoshino M, Murai T, Yonetsu T, Mejía-Rentería H, Kakuta T, Escaned J, Koo BK

Background and Objectives: Recent guideline recommends evaluation using of coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) in patients with functionally insignificant stenosis. We evaluated clinical implications of...
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SYNTAX Score and SYNTAX Score II Can Predict the Clinical Outcomes of Patients with Left Main and/or 3-Vessel Disease Undergoing Percutaneous Coronary Intervention in the Contemporary Cobalt-Chromium Everolimus-Eluting Stent Era

Kang J, Han JK, Kang DY, Zheng C, Yang HM, Park KW, Kang HJ, Koo BK, Kim HS

BACKGROUND AND OBJECTIVES: The impact of SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery score (SS) and SS II in patients who receive percutaneous coronary intervention with second-generation...
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The Effects of Preoperative Aspirin on Coronary Artery Bypass Surgery: a Systematic Meta-Analysis

Hwang D, Lee JM, Rhee TM, Kim YC, Park J, Park J, Ahn C, Song YB, Hahn JY, Kim KB, Lee YT, Koo BK

BACKGROUND AND OBJECTIVES: Aspirin plays an important role in the maintenance of graft patency and the prevention of thrombotic event after coronary artery bypass graft surgery (CABG). However, the use...
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