J Korean Neurosurg Soc.  1993 Nov;22(11):1175-1183.

Postoperative Intratumoral Injection of Bleomycin for Cystic Craniopharyngioma

• Yoon SH
• Choi JU
• Kim EY

Abstract

Surgical excision or irradiation of craniopharyngioma is problematic because both are often associated with high risk of complications. Three cases of cystic craniopharyngioma were subtotally removed by surgery and followed by repeated injection of bleomycin into the remaining tumor cavity as postoperative adjuvant therapy. With bleomycin injection, tumors were shrunk postoperatively in two cases out of three ut in one case cyctic portion became increased in size progressively which needed second operation and irradiation. Bleomycin injection could be considered as one of the reasonable alternative adjuvant therapies for incompletely removed cystic craniopharyngioma before radiation therapy.

Keyword

Chemotherapy; Craniopharyngioma; Bleomycin; Local injection

MeSH Terms

Bleomycin*
Craniopharyngioma*
Drug Therapy
Bleomycin