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Correlation Between Neuromelanin-Sensitive MRI and 18F-FP-CIT PET in Early-Stage Parkinson’s Disease: Utility of a Voxel-Wise Analysis by Using High-Spatial-Resolution MRI

Park S, Sung YH, Kim WR, Noh Y, Kim EY

Background and Purpose The correlation between dopamine transporter (DAT) imaging and neuromelanin-sensitive magnetic resonance imaging (NM-MRI) in early-stage Parkinson’s disease (PD) has not yet been established. This study aimed to determine...
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A Randomized, Double-Blind, Active-Control, Noninferiority, Multicenter, Phase 4 Study to Evaluate the Efficacy and Safety of Esomeprazole/Sodium Bicarbonate 20/800 mg in Patients with Nonerosive Gastroesophageal Reflux Disease

Park SH, Lee KN, Lee OY, Choi MG, Kim JH, Sung IK, Jang JY, Park KS, Chun HJ, Kim EY, Lee JK, Jang JS, Kim GH, Hong SJ, Lee YC, Choi SC, Kim HS, Kim TO, Baik GH, Jeon YC

Background/Aims: Efficacy of proton pump inhibitors is limited in patients with nonerosive reflux disease (NERD). The aim of this study was to comparatively evaluate the efficacy and safety of esomeprazole...
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Internal biliary stent in adult liver transplantation: a systematic review and meta-analysis

Kim JS, Lee TY, Kim EY, Kwon YK, Yoon YC

Background: Biliary complications in liver transplantation (LT) are a significant source of postoperative morbidly and mortality, and there is controversy as to whether the use of an internal stent (IS)...
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Artificial Intelligence-Based Identification of Normal Chest Radiographs: A Simulation Study in a Multicenter Health Screening Cohort

Yoo H, Kim EY, Kim H, Choi YR, Kim MY, Hwang SH, Kim YJ, Cho YJ, Jin KN

Objective: This study aimed to investigate the feasibility of using artificial intelligence (AI) to identify normal chest radiography (CXR) from the worklist of radiologists in a health-screening environment. Materials and Methods:...
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Epigallocatechin-3-gallate suppresses hemin-aggravated colon carcinogenesis through Nrf2-inhibited mitochondrial reactive oxygen species accumulation

Seok JH, Kim DH, Kim HJ, Jo HH, Kim EY, Jeong JH, Park YS, Lee SH, Kim DJ, Nam SY, Lee BJ, Lee HJ

Background: Previous studies have presented evidence to support the significant association between red meat intake and colon cancer, suggesting that heme iron plays a key role in colon carcinogenesis. Epigallocatechin-3-gallate...
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Characteristics of COVID-19 outbreaks and risk factors for transmission at an army training center in South Korea from June to August 2021

Cho UJ, Wang S, Yi S, Choi YH, Kim EY, Kim JA, Bae S, Yu J, Choi J, Park YJ

Objectives: It is crucial to establish the characteristics of coronavirus disease 2019 (COVID-19) outbreaks at army training centers to develop preventive measures. Therefore, this study aimed to determine the COVID-19...
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The Change in Circadian Rhythms in P301S Transgenic Mice is Linked to Variability in Hsp70-related Tau Disaggregation

Han SM, Jang YJ, Kim EY, Park SA

  • KMID: 2531123
  • Exp Neurobiol.
  • 2022 Jun;31(3):196-207.
  • doi: 10.5607/en22019
Circadian disruption often involves a neurodegenerative disorder, such as Alzheimer’s disease or frontotemporal dementia, which are characterized by intraneuronal tau accumulations. The altered sleep pattern and diurnal rhythms in these...
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Alterations of Functional Connectivity in Patients With Restless Legs Syndrome

Park KM, Kim KT, Kang KW, Park JA, Seo JG, Kim J, Chang H, Kim EY, Cho YW, oBotRSotKSRS

Restless legs syndrome (RLS) is a common neurological illness marked by a strong desire to move one’s legs, usually in association with uncomfortable sensations. Recent studies have investigated brain networks...
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Experiences of Nurses Caring for Hemodialysis Patients: A Qualitative Meta-Synthesis Study

Lee YN, Kim EY

Purpose: We aimed to systematically review and synthesize qualitative evidence on the experiences of nurses caring for hemodialysis patients. Methods: We used Noblit and Hare’s meta-ethnography. Seven databases (PubMed, EMBASE,...
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Influence of the Patient Safety Culture and Nursing Work Environment on Fall Prevention Activities of Hospital Nurses

Jung SY, Kim EY

Purpose: This study was conducted to identify the influence of patient safety culture and nursing work environment on fall prevention activities among hospital nurses. Methods: The participants were 177 nurses...
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ABT-737, a BH3 Mimetic, Enhances the Therapeutic Effects of Ionizing Radiation in K-ras Mutant Non-Small Cell Lung Cancer Preclinical Model

Lee JM, Kim HS, Kim A, Chang YS, Lee JG, Cho J, Kim EY

Purpose: Tumor radioresistance and dose-limiting toxicity restrict the curative potential of radiotherapy, requiring novel approaches to overcome the limitations and augment the efficacy. Here, we investigated the effects of signal...
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Tranexamic Acid Reduces Postoperative Blood Loss in Reverse Total Shoulder Arthroplasty

Park KY, Kim IB, Kim EY, Lee KS

Purpose: Tranexamic acid (TXA) can reduce perioperative blood loss and the frequency of blood transfusions in lower extremity surgery. On the other hand, the effects of TXA on reverse total...
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Protective effects of folic acid on colon carcino-genesis induced by azoxymethane in mice

Sohn JY, Kim EY, Jeong JH, Kim DJ, Nam SY, Lee HJ, Lee BJ

Colon cancer has been considered a leading cause of cancer-associated death. Folic acid is a vitamin necessary for cellular physiological functions and cell viability. However, the association between folic acid...
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Protecting Your Endoscopy Unit during the COVID-19 Pandemic

Jo HH, Kim EY

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Treatment Patterns of Type 2 Diabetes Assessed Using a Common Data Model Based on Electronic Health Records of 2000–2019

Lee KA, Jin HY, Kim YJ, Im YJ, Kim EY, Park TS

Background: Real-world data analysis is useful for identifying treatment patterns. Understanding drug prescription patterns of type 2 diabetes mellitus may facilitate diabetes management. We aimed to analyze treatment patterns of type...
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Liver Failure Has Higher IgG ABO Blood Group Isoagglutinin Titer than Kidney Failure

Choi S, Kim EY, Kim H, Cho D

Background: In ABO-incompatible (ABOi) solid organ transplantation, the minimization and management of isoagglutinin (IA) against donor ABO antigens between before and two weeks after transplantation is important for preventing hyper-acute...
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Effects of high-flow nasal cannula in patients with mild to moderate hypercapnia: a prospective observational study

Nam KH, Kang HK, Lee SS, Park SH, Kang SW, Hwang JJ, Park SY, Kim WY, Suh HJ, Kim EY, Seo GJ, Koh Y, Hong SB, Huh JW, Lim CM

Background: Evidence for using high-flow nasal cannula (HFNC) in hypercapnia is still limited. Most of the clinical studies had been conducted retrospectively, and there had been conflicting reports for the...
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The Association between Behavioral Risk Factors and Nontuberculous Mycobacterial Pulmonary Disease

Park Y, Kwak SH, Yong SH, Lee SH, Leem AY, Kim SY, Lee SH, Chung K, Kim EY, Jung JY, Park MS, Kim YS, Chang J, Kang YA

Purpose: We aimed to determine the relationship between environmental exposure and nontuberculous mycobacterial pulmonary disease (NTM-PD) in Korea. Materials and Methods: A group of 150 patients with NTM-PD and a control...
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Impact of 8-Week Bedside Ultrasound Training for Surgical Residents in the Intensive Care Unit of a Tertiary Care Hospital - a Pilot Study

Im KM, Kim EY

Purpose: Bedside ultrasound has become one of the most important non-invasive and readily available diagnostic tools, especially for critically ill patients. Despite the increasing usage and importance of bedside ultrasound,...
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Erratum to “Global and regional ventilation during high flow nasal cannula in patients with hypoxia”

Lee DH, Kim EY, Seo GJ, Suh HJ, Huh JW, Hong SB, Koh Y, Lim CM

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