Korean J Thorac Cardiovasc Surg.  2004 Jul;37(7):553-558.

Comparison of Clinical Outcomes of Off-pump versus On-pump Coronary Artery Bypass Grafting in Diabetes Patients

• Song SW
• Yoo KJ
• Lim SH
• Hong SC
• Cho SJ
• Chang BC
• Kang MS
• Shin HR

Abstract

BACKGROUND: Avoiding cardiopulmonary bypass (CPB) in coronary artery bypass grafting (CABG) has been known to reduce early mortality and morbidity. Diabetes Mellitus is a significant risk factor for adverse early and late outcomes after CABG. We compared the clinical results of off-pump CABG versus on-pump CABG in diabetes patients. MATERIAL AND METHOD: 682 patients (424 off-pump CABG and 258 on-pump CABG) underwent isolated coronary artery bypass grafting between January 2001 and June 2003. Data were collected 242 patient who had diabetes. Among them, 154 patients underwent off-pump CABG and 90 patients underwent on-pump CABG. We analyzed the preoperative risk factors and postoperative results between 2 groups. RESULT: Two groups did not show statistical differences in age, sex, coronary and operative risk factors. Operative time was significantly shorter in off-pump CABG, however, number of grafts was fewer in off-pump CABG. Postoperative inotropic usage was lower in off-pump CABG. Postoperative CK-MB level was lower in off-pump CABG, and ICU stay and ventilation time was significantly shorter in off-pump CABG. However, there was no statistical difference between 2 groups in operative mortality, reoperation rate, perioperative myocardial infarction, wound infection, renal failure, neurological complications and hospital stay.
CONCLUSION
Off-pump CABG group showed less myocardial damage and early recovery. We concluded that off-pump CABG is the more reasonable technique in diabetes patients although two techniques showed good results. The long-term follow up and prospective study may be warranted.

Keyword

Diabetes mellitus; Coronary artery bypass; Off-pump

MeSH Terms

Cardiopulmonary Bypass
Coronary Artery Bypass*
Coronary Vessels*
Diabetes Mellitus
Follow-Up Studies
Humans
Length of Stay
Mortality
Myocardial Infarction
Operative Time
Renal Insufficiency
Reoperation
Risk Factors
Transplants
Ventilation
Wound Infection