J Korean Assoc Oral Maxillofac Surg.  1999 Jan;25(1):54-60.

Case Reports Of Osteosarcoma In Mandible

Affiliations
  • 1Department of OMFS, Sanggae Paik Hospital, College of Medicine, Inje University, Korea.

Abstract

Sarcoma is a malignant tumor originated from bone, cartilage, fat tissue, nerve, blood vessel, bone marrow, endothelium, etc. and for this reason it exhibits considerable variation not only clinical but histologic appearance. Osteosarcoma occurs chiefly in young persons and in patients older than 40 years it is usually associated with Paget's disease, irradiated bone, multiple hereditary exostosis or polyostotoc fibrous dysplasia and sometimes with preceding trauma. Radiographically it is divided into three forms: an osteoblastic or sclerosing type, an osteolytic type, and mixed type. Histologically it is divided into osteoblastic type, chondroblastic type, fibroblastic type. The treatment of osteosarcoma is radical excision, combined chemotherapy but the prognosis is poor and overall 5-year survival rate is 20-40%. We present two different type sarcomas of 22-year-old male and 56-year-old male patients which we performed surgical excision, combined chemotherapy and radiation therapy.

Keyword

osteosarcoma; surgical excision

MeSH Terms

Blood Vessels
Bone Marrow
Cartilage
Chondrocytes
Drug Therapy
Endothelium
Exostoses
Fibroblasts
Humans
Male
Mandible*
Middle Aged
Nerve Tissue
Osteoblasts
Osteosarcoma*
Prognosis
Sarcoma
Survival Rate
Young Adult
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