Korean J Infect Dis.  2001 Dec;33(6):453-455.

Scrub Typhus in a Pregnant Woman: No Evidence of Intrauterine Infection

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mdohmd@snu.ac.kr
  • 2Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, Korea.

Abstract

Pregnancy with scrub typhus is a rare condition. A 30-year-old woman was infected with scrub typhus at the 35th week of gestation. She was treated successfully with azithromycin, and delivered her baby uneventfully. The baby developed no signs for scrub typhus, and thrived well. IgM antibodies to O. tsutsugamushi were undetectable in the baby's sera, and titers of IgG antibodies did not rise. The polymerase chain reaction of the cord blood for O. tsutsugamushi was also negative. We concluded that transplacental infection did not occur in this pregnant woman.

Keyword

Scrub typhus; Pregnancy; Vertical transmission; Azithromycin

MeSH Terms

Adult
Antibodies
Azithromycin
Female
Fetal Blood
Humans
Immunoglobulin G
Immunoglobulin M
Polymerase Chain Reaction
Pregnancy
Pregnant Women*
Scrub Typhus*
Antibodies
Azithromycin
Immunoglobulin G
Immunoglobulin M
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