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Clinical Score System to Differentiate Severe Fever with Thrombocytopenia Syndrome Patients from Patients with Scrub Typhus or Hemorrhagic Fever with Renal Syndrome in Korea

Heo DH, Kang YM, Song KH, Seo JW, Kim JH, Chun JY, Jun KI, Kang CK, Moon SM, Choe PG, Park WB, Bang JH, Kim ES, Kim HB, Park SW, Oh WS, Kim NJ, Oh MD

BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high mortality in East Asia. This study aimed to develop, for primary care providers, a prediction score...
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Facial diplegia as a delayed complication of scrub typhus

Baek JG, Hong HL, Park JH

A 64-year-old man presented with facial diplegia occurring 2 weeks after scrub typhus diagnosis. The serum scrub typhus antibody titer was elevated to 1:5120. Brain magnetic resonance imaging revealed contrast-enhancement...
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History of Tsutsugamushi Disease in Korea

Chung MH, Kang JS

Tsutsugamushi disease or scrub typhus in Korea was first officially reported in foreign soldiers in 1951 and in indigenous persons in 1986. However, the history is further prolonged. The book...
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Clinical and Laboratory Predictors associated with Complicated Scrub Typhus

Kim MH, Kim SH, Choi JH, Wie SH

BACKGROUND: Scrub typhus, a mite-borne disease caused by bites of Orientia tsutsugamushi-infected chiggers, is endemic in Asia-Pacific countries. In Korea, it is a seasonal disease prevalent in autumn and one...
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A Study on the Febrile Illness in Autumn among Farmers in Gyeongju-si: Scrub typhus, Leptospirosis, HFRS

Kim DS, Acharya D, Yoo SJ, Park JH, Lee K

OBJECTIVES: This study aimed to assess the status of Scrub typhus, Leptospirosis and HFRS(hemorrhagic fever with renal syndrome) among farmers with febrile illness. METHODS: We involved a total of 841 farmers...
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Pulmonary Artery Thrombosis Associated with Scrub Typhus

Cho JH, Lee CH

Scrub typhus is an acute febrile disease caused by Orientia tsutsugamushi, and the clinical course varies from mild and self-limiting to fatal. We describe a rare case of a pulmonary...
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Recent Increase of Human Granulocytic Anaplasmosis and Co-Infection with Scrub Typhus or Korean Hemorrhagic Fever with Renal Syndrome in Korea

Heo DH, Hwang JH, Choi SH, Jeon M, Lee JH, Lee JH, Hwang SD, Lee KA, Lee SH, Lee CS

We report 17 patients with human granulocytic anaplasmosis between January 2015 and September 2018 at two tertiary university hospitals in Korea. Monthly incidence peaked in May and June. Among these...
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Neuropathic Pain in Guillain-Barre Syndrome Associated with Scrub Typhus

Kang S, Lee SJ, Choi E

Guillain-Barre syndrome (GBS) is usually characterized by acute areflexic ascending paralysis with minimal sensory involvement. Only a few cases of GBS associated with scrub typhus have been reported. Previous case...
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Annual Fluctuation in Chigger Mite Populations and Orientia Tsutsugamushi Infections in Scrub Typhus Endemic Regions of South Korea

Kim SY, Gill B, Song BG, Chu H, Park WI, Lee HI, Shin EH, Cho SH, Roh JY

OBJECTIVES: Chigger mites are vectors for scrub typhus. This study evaluated the annual fluctuations in chigger mite populations and Orientia tsutsugamushi infections in South Korea. METHODS: During 2006 and 2007, chigger...
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The Eschar Size and Early Inoculation Lesion of Tsutsugamushi Disease on Jeju Island, Korea

Kim YH, Hyun W, Kim DP, Chung MH, Im JH, Baek JH, Lee JS, Kang JS

BACKGROUND: Tsutsugamushi disease, or scrub typhus, is an acute febrile illness caused by Orientia tsutsugamushi, which is followed by chronic latent infection. People who reside in areas endemic of tsutsugamushi...
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Co-Infection of Scrub Typhus and Human Granulocytic Anaplasmosis in Korea, 2006

Kim JH, Lee CS, Moon C, Kwak YG, Kim BN, Kim ES, Kang JM, Park WB, Oh MD, Park SW

BACKGROUND: Scrub typhus, severe fever with thrombocytopenia syndrome (SFTS) and human granulocytic anaplasmosis (HGA) are important arthropod-borne infectious diseases in Korea and share a common point that they are transmitted...
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Predictors of acute myocarditis in complicated scrub typhus: an endemic province in the Republic of Korea

Chin JY, Kang KW, Moon KM, Kim J, Choi YJ

BACKGROUND/AIMS: Scrub typhus is known as a self-limited infectious disease. Cardiac complication is uncommon and usually not life-threatening. Until now, few cases of fulminant myocarditis by scrub typhus have been...
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A Case of Scrub Typhus complicated with a Splenic Infarction

Durey A, Kwon HY, Park YK, Baek J, Han SB, Kang JS, Lee JS

We present a patient with scrub typhus complicated with a splenic infarction. A 40-year-old man visited the emergency medical center complaining of fever for the previous week. He had no...
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Mathematical Modeling for Scrub Typhus and Its Implications for Disease Control

Min KD, Cho SI

BACKGROUND: The incidence rate of scrub typhus has been increasing in the Republic of Korea. Previous studies have suggested that this trend may have resulted from the effects of climate...
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Histopathologic Finding of Perieschar Lesions in Tsutsugamushi Disease Shows Lymphocytic Vasculitis Mimicking Angiocentric Lymphoma

Jang MS, Park JB, Lee KH, Jang JY, Yang MH, Kim JH, Hwangbo H, Lee TG, Suh KS

BACKGROUND: Tsutsugamushi disease is an acute, febrile, infectious disease caused by Orientia tsutsugamushi. Several studies investigating the histopathologic findings of eschars in tsutsugamushi disease reported leukocytoclastic vasculitis and neutrophil infiltration...
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The Most Common Mite- and Tick-borne Infectious Diseases in Korea: Scrub Typhus and Severe Fever Thrombocytopenia Syndrome

Kim DY, Kim DM

The incidence of mite- and tick-borne infectious disease is increasing with climate change and the development of diagnostic tools. Tick-borne infectious diseases include Lyme disease, anaplasmosis, ehrlichiosis, severe fever with...
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A Case of Scrub Typhus Related Encephalopathy Presenting as Rapidly Progressive Dementia

Park JH, Jang JW, Lee SH, Oh WS, Kim SS

BACKGROUND: An infection known to be a major cause of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS). Rapidly progressive dementia is a neurological condition in which dementia progresses in...
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The clinical usefulness of serum procalcitonin level in patients with scrub typhus

Lee CS, Hwang JH, Lee JM, Lee JH

No abstract available.
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Severe Scrub Typhus with Hemophagocytic Lymphohistiocytosis Occurring in Summer

Ahn JS, Noh JH, Kim HR, Jung J, Jo JC, Lim JH, Jun JB

In Korea, scrub typhus usually occurs in October and November. Hemophagocytic lymphohistiocytosis (HLH) is a distinct clinical entity characterized by a high fever, pancytopenia, hepatosplenomegaly, histiocyte proliferation, and hemophagocytosis. We...
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Effects of clarithromycin treatment in scrub typhus in children: comparison with chloramphenicol and azithromycin

Lee M, Kim J, Jo DS

PURPOSE: Chloramphenicol and tetracycline are not recommended for treating scrub typhus in pediatric patients because of potential side effects, such as aplastic anemia or tooth discoloration. While clarithromycin has recently...
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