J Korean Radiol Soc.
2008 Jun;58(6):607-612. 10.3348/jkrs.2008.58.6.607.
Four Cases of Large Cell Neuroendocrine Carcinoma of the Stomach: Findings on CT and Barium Studies
- Affiliations
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- 1Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea. dichoi@smc.samsung.co.kr
- 2Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
- 3Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
- 4Department of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
- KMID: 2024543
- DOI: http://doi.org/10.3348/jkrs.2008.58.6.607
Abstract
- A large cell neuroendocrine carcinoma of the stomach is extremely rare. We have reviewed the medical records and imaging studies of the four patients that presented with a large cell neuroendocrine carcinomas of the stomach. On a barium study and CT imaging, a gastric large cell neuroendocrine carcinoma is depicted as an ulcerofungating tumor with minimal peritumoral infiltration and metastatic lymphadenopathy in the perigastric area. These findings are similar to findings for advanced gastric cancer, especially Borrmann type II. However, a gastric large cell neuroendocrine carcinoma is highly malignant with a significantly worse prognosis than a usual adenocarcinoma.
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