Korean J Gastrointest Endosc.  2009 Aug;39(2):93-96.

A Case of a Gastric Composite Tumor with an Adenocarcinoma and a Large Cell Neuroendocrine Carcinoma

  • 1Department of Gastroenterology, Department of Internal Medicine, College of Medicine,The Catholic University of Korea, Seoul, Korea. psheon5132@naver.com


A 55 year-old man was admitted with epigastric pain of one-month duration. We performed an esophagogastroduodenoscopy that showed the presence of a 3 cm sized polypoid mass at the lesser curvature side of the antrum. A biopsy demonstrated the presence of a neuroendocrine carcinoma of the stomach. A subtotal gastrectomy with D2 lymph node dissection was performed and the microscopic features of the resected specimen confirmed the diagnosis of a composite large cell neuroendocrine carcinoma with an adenocarcinoma of the stomach. A gastric neuroendocrine carcinoma is extremely rare and a composite neuroendocrine carcinoma with an adenocarcinoma of the stomach has been rarely reported. We report a case of a gastric composite tumor with an adenocarcinoma and a large cell neuroendocrine carcinoma.


Composite tumor; Neuroendocrine carcinoma; Adenocarcinoma
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