J Korean Neurol Assoc.  1991 Mar;9(1):116-119.

Paroxysmal Nocturnal Hemoglobinuria Presenting as Cerbral Venous Sinus Thrombosis and Acute Renal Failure: A Case Report

• Hong SH
• Bae JC
• Cho PZ

Abstract

Cerebral venous sinus thrombosis and acute renal failure are well known cornplications of paroxysmal nocturnal hemoglobinuria(PNH). 53 year old rnan was admitted to the hospital because of headache and gerleralized convulsion. Contrast enharlced CT scan revealed empty delta sign in superior sagital sinus and acute renal failure developed within 2 weeks of admissiorL The diagnosis of PNH depended on positive HAM test and low leukocyte alkaline phosphatase(LAP). The prognosis was relativley good on the treatrnent with anticoagulant, anticonvulsant, antiplatelets and steroid.

MeSH Terms

Acute Kidney Injury*
Diagnosis
Headache
Hemoglobinuria, Paroxysmal*
Humans
Leukocytes
Middle Aged
Prognosis
Seizures
Sinus Thrombosis, Intracranial*
Tomography, X-Ray Computed