Korean J Med.  2016 Feb;90(2):132-135. 10.3904/kjm.2016.90.2.132.

Paroxysmal Nocturnal Hemoglobinuria Presenting as Recurrent Jejunitis

Affiliations
  • 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. gisnhong@gmail.com

Abstract

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disorder characterized by chronic complement-mediated intravascular hemolysis, nocturnal hemoglobinuria, predisposition to thrombosis and secondary bone marrow failure. Small bowel ischemia is a complication of PNH but has not been reported to date in a Korean adult. We report here a case of PNH presenting as recurrent jejunitis. Despite the uncommon etiology, PNH should be considered in the differential diagnosis of patients with unexplained recurrent jejunitis.

Keyword

Jejunitis; Paroxysmal nocturnal hemoglobinuria; Thrombosis; Small bowel ischemia

MeSH Terms

Adult
Bone Marrow
Diagnosis, Differential
Hematopoietic Stem Cells
Hemoglobinuria
Hemoglobinuria, Paroxysmal*
Hemolysis
Humans
Ischemia
Thrombosis
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