J Korean Geriatr Psychiatry.  1999 Jun;3(1):22-31.

Senile Dementia;Diagnosis and Differential Diagnosis

  • 1Department of Psychiatry, Chung-Ang University Hospital, Seoul, Korea.


The auther tried to describe the diagnosis and differential diagnosis of senile dementia, especially Alzheimer's dementia (AD). AD is a clinicopathological manifestation, which patients are estimated as about 150 hundred thousands globally in 1997. The etiology of the AD is not cleared but the risk factors of the AD are known as old age, Down's syndrome and genetic factors. The diagnosis of the AD is based on exclusion criteria some years ago. But it is known that there are some distinghed clinical features through the clinical course of AD and physically peculiar features are found using neuroimaging technique. There are some distinguished changes found in the postmortem brain study of AD patients. The auther discussed the AD diagnosis process through AD differential diagnosis, mental status examination, functional global evauation, neuroimaging, electrophysiology, neuropathology and peripheral marker.


Alzheimer's dementia; Diagnosis; Differential diagnosis
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